摘要
真皮替代物（DS）的出现为深度皮肤缺损的治疗提供了一种新的选择，但DS血管化偏慢的问题一定程度上阻碍了其进一步的推广和使用。近年来，负压伤口疗法（NPWT）兴起，其在促进创面愈合方面的技术优势逐渐凸显。本文拟对NPWT促进DS血管化的可能机制及NPWT联合不同治疗方法对DS血管化的影响作-综述。
In clinical practice, skin defects resulted from various acute and chronic diseases occur frequently. Dermal substitute （DS） , known as dermal regenerative template, is used more and more widely, but the slow process of vascularization limits its clinical application. At present, there are many strategies developed to enhance the process of vascularization, such as modifying the structure of dermal scaffolds, prevascularization by seeding stem cells and/or endothelial cells. Recently, negative-pressure wound therapy （NPWT） emerged and rapidly became popular in promoting wound healing due to its intrinsic advantages. Furthermore, some researchers introduced this technique to accelerate the vaseularization process of DS. This paper represents a comprehensive overview on the efficiency of NPWT in different combination models, and the related mechanism.
出处
《中华烧伤杂志》
CAS
CSCD
北大核心
2017年第8期523-525,共3页
Chinese Journal of Burns
关键词
负压伤口疗法
新生血管化
病理性
伤口愈合
真皮替代物
Negative-pressure wound therapy
Neovascularization, pathologic
Wound healing
Dermal substitute
