摘要
目的 探讨心理干预联合格列齐特和西格列汀对胰岛素治疗血糖控制欠佳肥胖2型糖尿病患者的疗效。方法 将96例经胰岛素治疗后血糖仍控制不佳的肥胖2型糖尿病患者随机分为对照组与实验组,各48例,对照组采用格列齐特和西格列汀治疗,实验组在对照组基础上加用心理干预,治疗15周后,比较2组治疗前后空腹血糖值（FBG）、糖化血红蛋白（HbA1c）、餐后2 h血糖（2h PG）、空腹胰岛素（FIns）状况。结果 实验组较对照组FBG、HbA1c、2h PG、FIns明显降低,差异具有统计学意义（P〈0.05）。结论 采用心理干预联合格列齐特和西格列汀对胰岛素治疗血糖控制欠佳肥胖2型糖尿病患者进行治疗,可明显降低患者血糖水平,值得推广。
Objective To investigate the effect of psychological intervention combined with gliclazide and sitagliptin on the treatment of poorly obese obese patients with type 2 diabetes mellitus. Methods 96 obese patients with type 2 diabetes mellitus who had poor control of blood glucose after insulin treatment were randomly divided into control group and experimental group,48 cases in each groups. Gliclazide and sitagliptin （FBG）, glycosylated hemoglobin （HbA1c）, 2h postprandial blood glucose （2hPG）, fasting insulin （FIns） were measured before and after 15 weeks of treatment in the control group. situation. Results FBG, HbA1c, 2hPG and FIns were significantly lower in the experimental group than in the control group （P〈0.05）. Conclusion The combination of gliclazide and sitagliptin on the treatment of poorly obese type 2 diabetes mellitus with insulin treatment can significantly reduce the blood glucose level of patients and promote it.
出处
《中国生化药物杂志》
CAS
2017年第8期154-155,共2页
Chinese Journal of Biochemical Pharmaceutics
