摘要
目的探讨高强度聚焦超声(HIFU)消融治疗子宫肌瘤的临床疗效及安全性。方法采用HIFU消融治疗46例子宫肌瘤患者,通过核磁共振(MRI)测量治疗前瘤体体积及治疗后瘤体无灌注区体积计算消融率,并通过超声检测对比治疗前后瘤体体积大小变化,计算靶肌瘤缩小率;结合患者治疗前后子宫肌瘤症状评分判断治疗效果;记录患者治疗中及治疗后的不良反应。结果获HIFU治疗的46例患者中,靶肌瘤消融率为(77.79±11.94)%,治疗3个月后靶肌瘤缩小率为(39.90±11.14)%,且HIFU治疗中及治疗后并发症少。结论 HIFU消融为一种无创治疗技术,可安全、有效地治疗子宫肌瘤。
Objectives To investigate the clinical effect and safety of ablation with high intensity focused ultrasound( HIFU) for treating hysteromyoma. Methods Totally 46 patients with hysteromyoma were treated by ablation with HIFU. Tumor volume before treatment and area of no perfusion volume after treatment were measured by magnetic resonance imaging( MRI), and the ablation rate was recorded.Tumor volume was evaluated at before and after treatment, and the decreased rate of tumor volume was calculated by color doppler ultrasound. The efficacy also evaluated by hysteromyoma symptom score. The adverse reactions in and after treatment were recorded.Results In the 46 patients treated by ablation with HIFU,the tumor ablation rate was( 77. 79 ± 11. 94) %. 3 month after treatment,the tumor volume reduction rate was( 39. 90 ± 11. 14) %,and fewer complications after treatment were appeared. Conclusion Ablation with HIFU is a noninvasive technique for the safe and effective treatment of hysteromyoma.
作者
彭巧
王薇
Peng Qiao Wang Wei(Department of Gynaecology and Obstetrics, Chengdu Women and Children's Central Hospital, Chengdu, Sichuan, China 610091)
出处
《中国药业》
CAS
2017年第11期63-66,共4页
China Pharmaceuticals
关键词
子宫肌瘤
高强度聚焦超声消融
疗效
安全性
hysteromyoma
ablation with high intensity focused ultrasound
curative effect
safety