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探讨高效抗逆转录病毒用于治疗艾滋病患者临床不良反应及疗效动态 被引量:4

Study on Clinical Untoward Effect and Curative Effect Dynamics of Highly Active Antiretroviral Drugs for AIDS Patients
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摘要 目的分析高效抗逆转录病毒治疗艾滋病患者的临床疗效及不良反应。方法该次研究对象来源于该院2013年1月—2015年1月收治的艾滋病患者120例,均采用高效抗逆转录病毒治疗,探讨其临床疗效及不良反应。结果120例患者治疗有效率为74.2%,45.0%胃肠道反应,脂肪重分布、皮疹及骨髓抑制各占12.5%,肝肾功能、神经系统损伤及末梢神经炎各占6.7%,4.2%乳酸酸中毒。结论 HARRT治疗艾滋病效果较好,但不良反应较多,需密切监测,以保障患者用药安全性。 Objective To analyze the clinical Untoward effect and curative effect dynamics of highly active antiretroviral drugs for AIDS patients. Methods 120 cases of AIDS patients admitted and treated in our hospital from January 2013 to January 2015 were selected and treated with highly active antiretroviral drugs, and the clinical curative effect and Untoward effect were studied. Results Of 120 cases, the effective rate was 74.2%, gastrointestinal tract reaction accounted for 45.0%,and the fat redistribution, rash and bone marrow suppression accounted for 12.5%, and the liver and kidney function, nervous system damage and peripheral neuritis accounted for 6.7% and lactic acidosis accounted for 4.2%. Conclusion The HARRT in treatment of AIDS is better, but the Untoward effects are more, and we need to closely monitor it in order to ensure the medication safety.
出处 《中外医疗》 2017年第16期48-50,共3页 China & Foreign Medical Treatment
关键词 高效抗逆转录病毒 艾滋病 不良反应 Highly active antiretroviral drugs AIDS Untoward effects
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