摘要
目的探讨pkp结合抗骨质疏松药治疗骨质疏松性椎体压缩骨折的临床效果。方法选取山西省洪洞县中医医院骨科2014年1月~2016年12月收治的100例骨质疏松性椎体压缩骨折患者为研究对象,随机分为对照组和实验组,每组50例。对照组进行pkp治疗,实验组在pkp治疗的基础上结合抗骨质疏松药治疗。比较分析2组患者的相关临床指标。结果经过对应治疗后,实验组与对照组水泥渗漏率、骨水泥注入量指标差异无统计学意义。手术后,2组患者ODI指数以及VAS评分均显著优于治疗前,差异有统计学意义（P〈0.05）,患者锥体高度均得到较好恢复。经过14~24个月的随访后发现,实验组患者再骨折率为10.0%,显著低于对照组的24.0%,差异有统计学意义（P〈0.05）。结论 pkp结合抗骨质疏松药治疗骨质疏松性椎体压缩骨折临床效果较好,能够有效降低相邻节段锥体再骨折率,改善患者生活质量,具有临床进一步推广和应用的意义。
Objective To investigate the clinical effect of PKP combined with anti osteoporosis drugs in the treatment of osteoporotic vertebral compression fractures. Methods 100 cases of osteoporotic vertebral compression fractures treated in our hospital from January 2014 to December 2016 were compression fracture as the research object in the course of the study,and were randomly divided into control group and experimental group,with 50 cases in each group. Patients in the control group were treated with PKP,while the experimental group was treated with PKP combined with anti osteoporosis drugs. The related clinical indicators of the two groups were compared and analyzed. Results After the corresponding treatment,there was no significant difference between the experimental group and the control group in the rate of cement leakage and the amount of bone cement injection. After operation,the ODI index and VAS scoreof the two groups were significantly better than before treatment,the difference was statistically significant（ P〈 0. 05）,the patient＇s cone height was well recovered. After 14 to 24 months of follow-up found that,the fracture rate of the experimental group was10. 0%,significantly lower than the control group 24. 0%,the difference was statistically significant（ P 〈0. 05）. Conclusion PKP combined with anti osteoporosis drugs for the treatment of osteoporotic vertebral compression fractures has good clinical effect,can effectively reduce the adjacent segment cone fracture rate,improve the quality of life of patients,with further clinical promotion and application significance.
出处
《中国生化药物杂志》
CAS
2017年第7期233-234,共2页
Chinese Journal of Biochemical Pharmaceutics
关键词
PKP
抗骨质疏松药治疗
骨质疏松
椎体压缩骨折
临床效果
PKP
anti osteoporosis drug therapy
osteoporosis
vertebral compression fractures
clinical effect
