摘要
目的分析急性呼吸衰竭伴应激性高血糖给予新型肠内营养乳剂对其血糖及血清降钙素原的浓度影响。方法选取湖州市中心医院2013年4月~2016年8月收治的62例急性呼吸衰竭伴应激性高血糖患者,采用随机数字表法分为观察组（n=31）和对照组（n=31）,对照组给予肠内营养混悬液,观察组给予新型肠内营养乳剂,比较2组治疗前和治疗10 d后空腹血糖（FBG）、餐后2 h血糖（2 hPBG）、血清降钙素原（PCT）、白介素-6（IL-6）、C反应蛋白（CRP）水平,并统计2组不良反应发生情况。结果观察组治疗10 d后FBG、2 hPBG与对照组相比,明显较低,差异具有统计学意义（P〈0.05）;观察组治疗10 d后PCT浓度低于对照组,差异具有统计学意义（P〈0.05）;与对照组相比,观察组治疗10 d后IL-6、CRP明显较低,差异具有统计学意义（P〈0.05）;不良反应发生率组间比较差异无统计学意义（χ~2=0.267,P〉0.05）。结论急性呼吸衰竭伴应激性高血糖给予新型肠内营养乳剂可有效控制患者血糖水平,降低血清降钙素原的浓度。
Objective To analyze the effect of the new type of Enteral Nutritional Emulsion on the blood glucose and serum level of serum calcitonin in patients with acute respiratory failure. Methods 62 acute respiratory failure with stress hyperglycemia patients were selected and randomLy divided into observation group（ n = 31） and control group（ n = 31） in our hospital from April 2013 to August 2016,the control group was treated with Enteral Nutritional Suspension,the observation group was treated with New Enteral Nutritional Emulsion. We compared the two groups before treatment and after 10 days of fasting blood glucose（ FBG）,2 hour postprandial blood glucose（ 2hPBG）,serum procalcitonin（ PCT） and interleukin-6（ IL-6）,C reactive protein（ CRP） level,and statistics of the incidence of adverse reactions of the two groups. Results Comparing with the control group,the FBG and 2hPBG of the observation group was significantly lower than that of the control group after 10 days treatment,and the difference was statistically significant（ P 〈0. 05）; The concentration of PCT in the observation group was lower than that in the control group after 10 days,and the difference was statistically significant（ P 〈0. 05）; Comparing with the control group,the observation group after 10 days of treatment,CRP,IL-6 was significantly lower,the difference was statistically significant（ P 〈0. 05）; There was no significant difference in the incidence of adverse reactions between the two groups（ χ~2= 0. 267,P〉 0. 05）. Conclusion The new type of Enteral Nutritional Emulsion in the treatment of acute respiratory failure with stress hyperglycemia can effectively control the blood glucose level and reduce the concentration of serum calcitonin.
出处
《中国生化药物杂志》
CAS
2017年第7期73-75,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
急性呼吸衰竭伴应激性高血糖
血糖
血清降钙素原
新型肠内营养乳剂
acute respiratory failure with stress hyperglycemia
blood glucose
serum calcitonin
new type of enteral nutritional emulsion
