摘要
目的利用中医传承辅助平台(TCMISS V1.1)中的频数统计、关联规则、关联度分析、药物核心组合分析及无监督熵层次聚类算法,获得治疗糖尿病足中药熏洗处方的核心药物、核心组合及新处方。结果对筛选出的95个处方进行统计,使用频次前10位的是红花、桂枝、鸡血藤、当归、赤芍、川牛膝、川芎、透骨草、桃仁、黄芪。药物组合使用频次由高到低排序,前3组分别是"红花、桂枝","当归、红花","红花、鸡血藤"。并挖掘出治疗糖尿病足的中药熏洗方的核心组合16个和8首可能具有临床价值的新处方。结论目前治疗糖尿病足的中药熏洗方多以活血止痛、舒筋通络药为主,并通过数据挖据初步探索出了中药熏洗处方的主要药物组成为当归、红花、桂枝、黄芪、川芎、透骨草、赤芍、桃仁、乳香、没药、鸡血藤、川牛膝等。根据不同证型可以进一步探讨新方的临床价值。
Objective To use TCM inheritance auxiliary system （TCMISS V1. 1） in the frequency statistics, association rules, correlation analysis , drug core combination analysis and unsupervised hierarchical clustering algorithm to obtain the entropy , traditional Chinese medicine in the treatment of diabetic foot washing prescription drugs, smoked core core combinations and new prescription. Results The statistics of the 95 prescriptions , the frequency of use of the top 10 are safflower , angelica , cassia twig , Caulis Spatholobi , radix paeoniae rubra, Rhizoma Chuanxiong, Radix cyathulae, lopseed, peachseed, huangqi. Combination of drugs use frequency from high to low ranking , the first 3 groups were＂safflower Guizhi＂,＂angelica , safflower＂,＂safflower , Caulis Spatholobi＂. And dig out the core combination of herbal fumigation and washing prescription for treating diabetic foot , 16 and 8 new prescriptions that may have clinical value. Conclusion The traditional Chinese medicine in the treatment of diabetic foot fumigation in Huoxue Zhitong, Shujin Tongluo medicine , and through data mining initial y explored the main drug fumigation of Chinese medicine prescription composition：Angelica , safflower , astragalus , Guizhi , Rhizoma Chuanxiong , radix paeoniae rubra , lopseed , walnuts , milk incense , myrrh , Caulis Spatholobi. Cyathula etc.. The clinical value of the new method can be further explored according to different syndrome types.
出处
《云南中医学院学报》
2017年第3期87-90,共4页
Journal of Yunnan University of Traditional Chinese Medicine
基金
上海市科学技术委员会科研计划项目(16401902200)
关键词
糖尿病足
中药熏洗
数据挖掘
用药规律
diabetic foot
Chinese herbal fumigation and washing
data mining
medication regularity
