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血栓抽吸盐酸替罗非班在急性心肌梗死急诊介入治疗中的临床应用

Clinical application of thrombus aspiration with tirofiban hydrochloride in emergency interventional treatment of acute myocardial infarction
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摘要 目的探讨在急性心肌梗死急诊介入治疗患者中实施盐酸替罗非班介入治疗的临床效果。方法取2013年9月到2016年9月间本院收治的300例急性心肌梗死患者进行研究,采取随机数表法将患者分为介入组(n=150)和干预组(n=150),对所有介入组患者实施急诊介入治疗,对所有干预组患者在介入治疗前实施盐酸替罗非班治疗,统计分析两组患者的治疗效果。结果干预组患者CKMB峰值时间、CKMB峰值、TIMI3级发生率及LVEF、LVDd与介入组相比明显较优,术后心绞痛发生率与介入组相比明显较低,P<0.05。结论在急性心肌梗死急诊介入治疗患者中实施盐酸替罗非班的临床效果优良。 Objective To investigate the clinical effect of tirofiban hydrochloride interventional treatment in patients with acute myocardial infarction. Methods A total of 300 patients with acute myocardial infarction who were admitted to our hospital from September 2013 to September 2016 were enrolled and randomly divided into interventional treatment group and intervention group using a random number table, with 150 patients in each group. The patients in the interventional treatment group were given emergency interventional treatment, and those in the intervention group were given tirofiban hydrochloride before interventional treatment. The clinical outcome was analyzed for both groups.Results Compared with the interventional treatment group, the intervention group had significantly better results of time to peak of CKMB, peak of CKMB, incidence rate of grade 3 thrombolysis and thrombin inhibition in myocardial infarction, left ventricular ejection fraction, and left ventricular end-diastolic diameter, as well as a significantly lower incidence rate of postoperative angina pectoris(P 0.05). Conclusion Tirofiban hydrochloride used in emergency interventional treatment has a good clinical effect in patients with acute myocardial infarction.
作者 黄艳 HUANG Yah(Qianjiang Central Hospital, Chongqing 409000, Chin)
出处 《心血管病防治知识(学术版)》 2017年第6期28-30,共3页 Prevention and Treatment of Cardiovascular Disease
关键词 急性心肌梗死 急诊介入治疗 盐酸替罗非班 Acute myocardial infarction Emergency interventional treatment Tirofiban hydrochloride
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