摘要
目的探讨北京市居民日常行为、生活习惯、精神状态等对甲状腺结节的影响。方法在北京市西城、朝阳、门头沟和顺义区各选取1家体检机构，采用分层抽样分析的方法对在当地居住15年以上，年龄在45-50岁，不知道自己是否有甲状腺结节的一般体检人群进行问卷调查。使用1：1病例对照研究方法分析男性和女性人群中手机使用时间、锻炼情况、睡眠情况、精神紧张与甲状腺结节的关系。采用Logistic回归进行各因素与甲状腺结节关系的单因素分析，再对单因素分析中有统计学意义的影响因素进行多因素分析。结果甲状腺结节总检出率为35．06％（331／944），男性和女性分别为27．91％（144／516）和43．69％（187／428），女性检出率高于男性（X^2=25．60，P〈0．05）。Logistic回归分析显示，在男性和女性人群中，精神紧张[男、女：比值比（OR）=2．106、1．653，95％置信区间（CI）：1．158～3．831、1．042-2．622]和使用手机〉3h（男、女：OR=12．863、5-315，95％凹：1．540-107．444、1．359～20．794）是甲状腺结节的危险因素。结论甲状腺结节的发生可能与精神状态及长时间使用手机有关，但其作用机制仍需进一步探索。
Objective To investigate the effect of daily behavior, life habits, mental status of the resident population in Beijing City on thyroid nodules. Methods A questionnaire survey was conducted using stratified sampling method to investigate the resident population in physical examination organization of Xicheng, Chaoyang, Mentougou and Shunyi districts, who lived in Beijing for more than 15 years, ages between 45 - 50 years old, and they did not know whether suffered from thyroid nodules. A 1 ： 1 case-control study was used to analyze the relationships between thyroid nodules and mobile phone using time, exercise, sleep and mental stress in males and females. Logistic regression analysis was used to analyze relationships between various factors and thyroid nodule in single factor analysis, and if the influence factors in the single factor analysis had statistical significance they will be further analyzed in the multiple factors analysis. Results The total prevalence of thyroid nodules was 35.06% （331/944）, males and females were 27.91% （144/516） and 43.69% （187/428）, respectively. The prevalence of female was higher than that of male （X^2 = 25.60, P 〈 0.05）. Logistic regression analysis showed that mental stress （males, females： OR = 2.106, 1.653, 95%Ch 1.158 - 3.831, 1.042 - 2.622） and using the phone 〉 3 h （males, females： OR = 12.863, 5.315, 95%CI： 1.540 - 107.444, 1.359 - 20.794） were risk factors for thyroid nodules in the male and female populations. Conclusion The occurrence of thyroid nodules maybe related to mental status and using the phone for a long time, but its mechanism needs to be further explored.
出处
《中华地方病学杂志》
CSCD
北大核心
2017年第7期524-527,共4页
Chinese Journal of Endemiology
