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乳腺癌中医辨证分型与肿瘤标志物的相关性研究

Study on the Correlation between TCM Syndrome Differentiation and Tumor Markers in Breast Cancer
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摘要 目的探讨乳腺癌患者不同中医证型与肿瘤标志物的相关性。方法对312例乳腺癌患者中医辨证分型与肿瘤标记物进行统计分析。结果 312例乳腺癌患者中,冲任失调证,气血双亏、邪毒内陷证的血清肿瘤标志物CEA、CA-125、NSE水平较高(P<0.05);肝气郁结证,气血双亏、邪毒内陷证的血清肿瘤标记物CA-153、Ferritin水平较高(P<0.05)。而AFP各组间差异无统计学意义(P>0.05)。结论肿瘤标志物浓度的差异可反映乳腺癌患者本虚及标实的情况,研究中医辨证分型与肿瘤标志物的浓度,可为中医辨证分型、立法方药提供依据,对患者积极的进行早期预防及干预,提高患者生活质量,延长患者生命周期有积极的指导意义。 Objective To explore the correlation between different TCM syndrome differentiation and tumor markers in breast cancer. Methods TCM syndrome differentiation and tumor related antigen of 312 breast cancer patients were studied by review analysis. Results The levels of blood serum tumor marker CEA, CA125, NSE of imbalance of Ren channels syndrome, deficiency of qi and blood, pathogenic toxin depression syndrome were higher (P〈0.05) . The levels of blood serum tumor marker CA153, stagnation of liver qi, deficiency of qi and blood, pathogenic toxin depression syndrome was highly (P〈0.05) . The levels of blood serum tumor marker AFP was not statistically significant (P〈0.05) . Conclusion The change of serum tumor markers can reflect the breast cancer's asthenia and sthenia, study the correlation between TCM syndrome differentiations, can provide evidence on TCM syndrome differentiation and Legislation prescription of breast cancer, so as to make the positive intervention treatment, therefore improve the quality of life and extend survival time.
作者 陈瑾 李艺
出处 《中国中医药现代远程教育》 2017年第12期58-59,共2页 Chinese Medicine Modern Distance Education of China
关键词 乳腺癌 肿瘤标志物 中医辨证分型 乳岩 breast cancer tumor markers TCM syndrome differentiation
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