摘要
目的:探讨葱白提取物对动脉粥样硬化兔的血脂代谢的影响。方法:将新西兰白兔32只随机分为四组(n=8),正常对照组普食喂养,空白模型组、辛伐他汀组、葱白提取物组均喂食高脂食物。药物分别给予博心通胶囊、予辛伐他汀干预,实验周期8周,实验验结束后检测各组血脂水平。结果:空白模型组兔TC、TG、LDL、apo B较正常对照组明显升高(P<0.01),治疗后与正常对照组相比辛伐他汀组及葱白提取物组均明显下降(P<0.05),但葱白提取物组优于辛伐他汀组(P<0.05);空白模型组兔HDL、apo A1较正常对照组明显降低(P<0.01),治疗后与正常对照组相比辛伐他汀组及葱白提取物组均明显升高(P<0.05),但葱白提取物组优于辛伐他汀组(P<0.05)。结论:葱白提取物可以有效调节动脉粥样硬化兔血脂水平。
Objective ： To study the effect of fistular onion stalk extract on the atherosclerotic rabbits. Method： Thirty - two New Zealand white rabbits were randomly divided into four groups（ ti = 8 ） . The normal control group were fed with water; the blank model group,the simvastatin group and the fistular onion stalk extract group were fed with high - fat diets, the drugs were simvastatin and fistular onion stalk extract. Lipid levels were evalued when the 8 - weeks experiment ended. Results： The TC, TG, LDL, apoB levels in the blank model group were higher than the normal control group （P〈0. 01） ,which in the simvastatin group and the fistular onion stalk extract group were lower than that in the normal control group（F 〈0.05）. The fistular onion stalk extract group was superior to the simvastatin group. The DHL,apoAl levels in the blank model group were lower than the normal control group （P 〈0. 01） ,which in the simvastatin group and the fistular onion stalk extract group were higher than that in the normal control group（P 〈0.05） ,aslo the fistular onion stalk extract group was superior to the simvastatin group. Conclusion： Fistular onion stalk extract can effectively regulate blood lipid in the atherosclerotic rabbits.
出处
《江西中医药大学学报》
2017年第4期79-80,91,共3页
Journal of Jiangxi University of Chinese Medicine
基金
武汉市卫生局基金项目(WZ10C03)
关键词
葱白提取物
动脉粥样硬化
兔
血脂
Fistular Onion Stalk Extract
Atherosclerosis
Rabbit
Blood Lipid
