摘要
目的探讨整肠生在腹盆腔放疗中对急性放射性肠炎的预防作用。方法 211例Ⅱb-Ⅲb期宫颈癌行放射性治疗的患者随机分为观察组(n=109)和对照组(n=102),两组患者均行三维适形放射治疗,放疗剂量45~50Gy。观察组给予整肠生与康复新液联合使用:整肠生0.5g/次,一日三次,康复新液10mL/次,一日三次,对照组给予康复新液10mL/次,一日三次,比较两组治疗期间急性放射性肠炎发生率以及发生时间。结果急性放射性肠炎的发生率,观察组vs对照组为8.3%vs 20.6%,差异有统计学意义(P=0.008),且观察组出现急性放射性肠炎的时间迟于对照组,但差异无统计学意义。结论整肠生联合康复新液在预防急性放射性肠炎的发生方面效果显著,可用于临床治疗。
Objective To observe the effect of Bacillus Licheniformis Capsule,Live on preventing acute radiation enteritis in abdominopelvic radiotherapy. Methods Two hundred and eleven cases of Ⅱb-Ⅲb cervical cancer with radiotherapy were randomly divided into observation group（n=109）or control group（n=102）.Both groups were given three-dimensional conformal radiotherapy at a dose of 45~50 Gy.In addition,the observation group was given Bacillus Licheniformis Capsule,Live 0.5 g tid combined with Kangfuxin liquid 10 mL tid,while the control group was given Kangfuxin liquid 10 mL tid alone.The incidence and onset time of acute radiation enteritis were compared between the two groups.Results The incidence of acute radiation enteritis was 8.3% vs 20.6% in the observation group vs the control group,with significant difference（P〈0.05）,and the onset time of acute radiation enteritis in the observation group was later than that in the control group,but with no statistically significant difference.Conclusion Bacillus licheniformis combined with Kangfuxin liquid can effectively prevent the occurrence of acute radiation enteritis.
作者
杜振华
潘雪
DU Zhenhua PAN Xue(Department of Obstetrics and Gynecology, Shengjing Hospital Of China Medical University, Shenyang, Liaoning 110004, China)
出处
《中国微生态学杂志》
CAS
CSCD
2017年第6期715-717,共3页
Chinese Journal of Microecology
关键词
整肠生
宫颈肿瘤
放射疗法
急性放射性肠炎
Bacillus Licheniformis Capsule, Live
Uterine cervical neoplasm
Radiotherapy
Acute radiation enteritis
