摘要
银杏Ginkgo biloba为银杏科银杏属落叶乔木,是世界范围内应用最广泛的天然药物之一。银杏含多种活性成分,具有抗氧化、抗凋亡、改善脑血流、神经保护、抑制血小板活性等多种药理作用,用于心脑血管疾病、阿尔茨海默症、动脉粥样硬化、癌症、哮喘、非酒精性脂肪肝、糖尿病并发症等疾病的治疗。就银杏药理作用研究的新进展进行综述,以期为新药研发人员和临床医生提供更多的银杏药理资料,进而为新药研究提供依据。
Ginkgo biloba L.is one of the most widely used natural medicines.Ginkgo biloba contains a variety of active components.Ginkgo biloba has many pharmacological effects,especially anti-oxidation,anti-apoptosis,improvement of cerebral blood flow,neuroprotection,inhibition of platelet activity and so on.Ginkgo biloba can be used in the treatment of cardiovascular and cerebrovascular diseases,Alzheimer＇s disease,atherosclerosis,cancer,asthma,nonalcoholic fatty liver disease,diabetes complications,and other diseases.In this review,the recent progress in the research of pharmacology of Ginkgo biloba was reviewed in order to provide more information on the pharmacological action of Ginkgo biloba and the basis for new drug research.
出处
《药物评价研究》
CAS
2017年第6期731-741,共11页
Drug Evaluation Research
基金
国家自然科学基金青年项目(81503342)
中国博士后基金面上项目(2016M591967)
关键词
银杏
心脑血管疾病
动脉粥样硬化
癌症
非酒精性脂肪肝
哮喘
糖尿病并发症
cardiovascular and cerebrovascular diseases
atherosclerosis
cancer
nonalcoholic fatty liver disease
asthma
diabetic complication
