摘要
原发性醛固酮增多症（简称原醛症）是常见的继发性高血压之一。血浆醛固酮浓度（PAC）/血浆肾素活性（PRA）比值是当前临床上常用的原醛症筛查方法，但PRA仅间接反映血浆肾素水平。近年来，采用全自动化学发光法可直接测定血浆肾素浓度（PRC），且具有稳定性好、操作简便、影响因素少等优点。本文简单介绍血浆肾素、醛固酮的测定方法，并对PAC/PRA、PAC/PRC比值在原醛症筛查中的价值进行比较和评价。
Primary aldosteronism （PA） is one of the most common causes of secondary hypertension. plasma aldosterone concentration （PAC） /plasma renin activity （PRA） ratio is widely used in clinical practice. However, PRA reflects the level of plasma renin indirectly. In recent years, plasma renin concentration （PRC） has been measured by automatic chemiluminescence immunoassay, which is more stable, convenient and with less confounding factors than conventional renin activity. This review briefly introduces methods of examining PRA, PRC and PAC, and compares the value of PAC/PRC ratio with PAC/PRA ratio in PA detection.
出处
《中华内分泌外科杂志》
CAS
2017年第3期245-248,共4页
Chinese Journal of Endocrine Surgery
基金
国家自然科学基金（81170751,81370954,81200294）
关键词
血浆肾素浓度
浆醛固酮浓度
原发性醛固酮增多症
Plasma renin concentration
Plasma aldosterone concentration
Primary aldosteronism
