摘要
为了提高水中微量抗生素的检出限,用吸水树脂建立了一种高效、快速的样品现场前处理方法。以磺胺甲恶唑(SMX)、四环素(TC)和土霉素(OTC)为研究对象,以水溶液中3种抗生素浓缩后的残留率为指标,通过正交实验筛选出吸水树脂的最优合成方案,并考察了溶液pH值对抗生素残留率的影响。结果表明,当交联剂和引发剂含量为0.2%和3.5%,模板与单体质量比为1∶6,中和度75%时,吸收树脂对水中SMX和TC的浓缩效果最好,残留率可达(137.12±0.42)%和(113.47±15.74)%;当交联剂和引发剂含量为0.2%和1.9%,模板与单体质量比为1∶10,中和度为70%时,吸收树脂对水中OTC的浓缩效果最好,残留率可达(79.91±4.99)%。当pH=1时,方案A2B2C3D1浓缩SMX、TC、OTC的残留率可达(125.87±19.20)%,(113.81±10.93)%和(104.66±0.71)%。吸水树脂能成倍提高水中抗生素浓度;调节pH值,可提高水中抗生素的残留率。
A highly efficient,rapid sample pretreatment method was established with water-absorbing resin to improve the detection limit of trace antibiotics in water.Sulfamethoxazole （SMX）,tetracycline （TC） and oxytetracycline （OTC） were selected as the research objects in this research.The optimize schemes were sieved out through orthogonal experiment based on the rate of antibiotic residues in water after treatment.The effect of pH value on the rate of antibiotic residues was also investigated.When the content of cross-linker and initiator agent contents set at 0.2% and 3.5%,the template and monomer ratio fixed at 1∶6（m/m）,neutralization kept 75%,the residual rate of SMX and TC in solution reached to （137.12±0.42）% and （113.47±15.74）% after using water-absorbing resin.When the the content of cross-linker and initiator agent contents set at 0.2% and 1.9%,the template and monomer ratio fixed at 1∶10 （m/m）,neutralization kept 70%,the residual rate of OTC in solution reached to （79.91±4.99）% after water adsorbed by water-absorbing resin synthetic with the schemes.When the pH value is 1,the residual rate of SMX,TC and OTC in solution reached to （125.87±19.20）%,（113.81±10.93）% and （104.66±0.71）% after using water-absorbing resin,respectively.Meanwhile,concentrating efficiency of water-absorbing resin to antibiotics could be adjusted by the pH value in solution.
出处
《应用化工》
CAS
CSCD
北大核心
2017年第6期1218-1221,共4页
Applied Chemical Industry
基金
国家自然科学基金(41361072)
关键词
吸水树脂
样品前处理
浓缩
磺胺甲恶唑
四环素
土霉素
正交实验
water-absorbing resin
pretreatment method
concentration
sulfamethoxazole
tetracycline
oxytetracycline
orthogonal experiment
