摘要
目的:观察耳穴压豆疗法对妇科恶性肿瘤患者化疗引起恶心呕吐的治疗作用及其对血清5-羟色胺(5-HT)的影响。方法:将70例行化疗的妇科恶性肿瘤患者随机分为2组,2组均给与常规的处理,对照组不予其他任何止呕治疗,观察组在基础支持的基础上加用耳穴压豆法治疗。观察2组恶心呕吐反应情况,并检测患者血清5-HT水平。结果:治疗后,观察组出现恶心呕吐者22例,对照组出现恶心呕吐者30例,2组比较,差异有统计学意义(P<0.05);观察组急性恶心呕吐程度情况比较,第1天、第2天时2组比较,差异均有统计学意义(P<0.01);但2组其他观察时点情况比较,差异均无统计学意义(P>0.05)。化疗后,2组5-HT值均较化疗前有所升高,差异均有统计学意义(P<0.05);2组化疗后血清5-HT比较,差异无统计学意义(P>0.05)。结论:耳穴压豆能有效减轻化疗所致延迟性恶心呕吐,但尚不能证实其能降低血清5-HT。
Objective：To observe the effect of pressing ear acupoints with beans therapy on post-chemotherapy nausea and vomiting of Gynecologic malignant tumor patients, and its effect on serum 5-hydroxytryptamine（5-HT）. Methods ：Selected 70 post-chemotherapy patients with gynecologic malignant tumor,and divided them into two groups randomly. The two groups were both given routine treatment,and the control group was not given other treatment for antiemetic,while the observation group was given pressing ear acupoint with beans therapy based on the routine treatment. Observed nausea and vomiting,and detected serum 5-HT level of the two groups. Results ：After treatment,there were 22 cases and 30 cases occurred nausea and vomiting in the observation group and the control group respectively, the difference being significant（P〈0.05）;Compared degree of acute nausea and vomiting of the two groups,the difference in the first day and the second day both being significant（P〈0.01）;But the difference of other occasions was not significant（P〉0.05）. After chemotherapy,score of 5-HT of the two groups were both higher than those before treatment,the difference being significant（P〈0.05）;and the difference was not significant when the score of the two groups were compared（P〉0.05）. Conclusion：Pressing ear acupoints with beans can relieve delayed nausea and vomiting effectively,but it has not been prove if it can reduce 5-HT.
出处
《新中医》
CAS
2017年第6期110-112,共3页
New Chinese Medicine
基金
广东省中医药局科研课题(20142055)
关键词
恶心呕吐
化疗后
妇科
恶性肿瘤
耳穴压豆
血清5-羟色胺(5-HT)
Nausea and vomiting
Post-chemotherapy
Gynecologic
Malignant tumor
Pressing ear acupoints with beans
Serum 5-hydroxytryptamine（5-HT）
