摘要
目的:探讨升降散加减联合普瑞巴林治疗脊髓损伤后神经性疼痛的临床疗效。方法:将42例脊髓损伤后神经性疼痛患者随机分为治疗组和对照组各21例。治疗组口服升降散加味及普瑞巴林,对照组单纯口服普瑞巴林,疗程均为20天。记录患者治疗前后疼痛视觉模拟评分法(VAS)评分及现存疼痛强度(PPI)评分,并统计2组临床疗效。结果:临床有效率治疗组为85.71%,对照组为76.19%,2组比较,差异无统计学意义(P>0.05)。治疗后治疗组PPI及VAS评分均低于对照组(P<0.05)。结论:升降散加味联合普瑞巴林治疗可有效减轻脊髓损伤后神经性疼痛,疗效优于单纯普瑞巴林治疗。
Objective：To observe the clinical effect of modified Shengjiang san combined with Pregabalin for neuropathic pain after spinal cord injury. Methods：Selected 42 patients with neuropathic pain after spinal cord injury and divided them into the treatment group and the control group being 21 cases in each. The treatment group was given oral modified Shengjiang san combined with Pregabalin,while the control group was given oral Pregabalin only. Treatment both lasted for twenty days.Recorded scores of visual analogue scale（VAS） and present pain intensity（PPI） of patients before and after treatment, and analyzed clinical effect of the two groups. Results ： The total effective rate was 85.71% in the treatment group and was76.19% in the control group,the difference being not significant（P〉0.05）. After treatment,scores of PPI and VAS of the treatment group were both lower than those of the control group（P〈0.05）. Conclusion：Modified Shengjiang san combined with Pregabalin can relieve neuropathic pain after spinal cord injury effectively,which has better curative effect than use Pregabalin only.
出处
《新中医》
CAS
2017年第6期66-68,共3页
New Chinese Medicine
基金
广东省中医药局科研立项项目(20151049)
关键词
脊髓损伤
神经性疼痛
中西医结合疗法
升降散
普瑞巴林
Spinal cord injury
Neuropathic pain
Integrated Chinese and western medicine therapy
Shengjiang san
Pregabalin
