摘要
目的研究三磷酸腺苷与精索静脉结扎术联合治疗小儿原发性精索静脉曲张疾病的临床效果。方法选取浙江大学医学院附属儿童医院小儿泌尿外科2014年5月~2016年5月收治的小儿原发性精索静脉曲张疾病患儿80例,依据随机数字表法将这些患儿分为三磷酸腺苷与精索静脉结扎术联合治疗组(联合治疗组,n=40)和精索静脉结扎术治疗组(单独治疗组,n=40)2组,对2组患儿的术后疼痛评分、胃肠功能恢复时间、住院时间、住院费用、并发症发生情况及复发情况进行统计分析。结果联合治疗组患儿的术后疼痛评分、住院费用均显著低于单独治疗组(P〈0.05),胃肠功能恢复时间、住院时间均显著短于单独治疗组(P〈0.05),并发症发生率2.5%(1/40)显著低于单独治疗组17.5%(7/40)(P〈0.05),复发率2.5%(1/40)显著低于单独治疗组10.0%(4/40)(P〈0.05)。结论三磷酸腺苷与精索静脉结扎术联合治疗小儿原发性精索静脉曲张疾病的临床效果较单独精索静脉结扎术治疗好,值得在临床推广。
Objective To study the clinical effect of adenosine triphosphate and spermatic vein ligation combined treatment of children with primary varicocele disease.Methods80 cases of children with primary varicocele disease who were treated in pediatric surgery department of Hangzhou City Yuhang District MCH from May 2014 to May 2016 were selected, these children were divided into adenosine triphosphate and spermatic vein ligation combined treatment group (combined treatment group, n= 40) and spermatic vein ligation treatment group (monotherapy group, n=40) two groups according to the random number table, the postoperative pain score, gastrointestinal recovery time, hospital stay, cost of hospitalization, incidence of complications and recurrence of the two groups were statistically analyzed.ResultsThe postoperative pain score and hospitalization cost of the combined treatment group were significantly lower (P〈0.05), the gastrointestinal function recovery time and hospital stay were significantly shorter (P〈0.05), the incidence of complications 2.5% (1/40) was significantly lower than the monotherapy group 17.5% (7/40) (P〈0.05), the recurrence rate 2.5% (1/40) was significantly lower than the monotherapy group 10.0% (4/40) (P〈 0.05).ConclusionThe clinical effect of adenosine triphosphate and spermatic vein ligation combined treatment of children with primary varicocele disease is better than spermatic vein ligation treatment alone, so is worthy of promotion in the clinical.
出处
《中国生化药物杂志》
CAS
2017年第5期71-73,共3页
Chinese Journal of Biochemical Pharmaceutics
基金
杭州市卫生科技计划项目(2015B34)