摘要
目的观察十三味和中丸联合针刺治疗肝胃不和型功能性消化不良(functional dyspepsia,FD)的临床疗效。方法选取肝胃不和型FD患者60例,随机分为治疗组和对照组各30例,治疗组予以十三味和中丸配合针刺治疗,对照组予以多潘立酮口服治疗,疗程均为4周。结果治疗4周后,治疗组总体疗效优于对照组,差异具有统计学意义(P<0.05)。两组各项临床症状均明显改善,但治疗组在改善胃胀、胃痛、喜太息、纳差、早饱、上腹部烧灼感、胁肋窜痛和大便不爽方面明显优于对照组(P<0.05)。治疗4周后和1个月后随访时,两组SF-36总分均明显提高(P<0.05),但治疗组SF-36总分明显高于对照组(P<0.05)。结论十三味和中丸联合针刺治疗方法能明显改善肝胃不和型FD患者的临床症状,提高其生活质量。
Objective To investigate the clinical effect of Shisanwei Hezhong Pill combined with acupuncture in the treatment of functional dyspepsia （FD） of incoordination between liver and stomach.Methods A total of 60 patients with FD of incoordination between liver and stomach were enrolled and randomly divided into treatment group and control group, with 30 patients in each group. The patients in the treatment group were given Shisanwei Hezhong Pill combined with acupuncture, and those in the control group were treated with oral domperidone. The course of treatment was 4 weeks for both groups. Results After 4 weeks of treatment, the treatment group had a significantly better clinical outcome than the control group （P〈0.05）. Both groups had significant improvements in clinical symptoms, and compared with the control group, the treatment group had significantly better improvements in stomach distension, stomachache, deep sigh, poor appetite, early satiety, upper abdominal burning sensation, scurrying pain in the lateral thorax, and discomforts in defecation （P〈0.05）. Immediately and at 1 month after 4-week treatment, both groups had a significant increase in SF-36 score （P〈0.05）, and the treatment group had a significantly higher SF-36 score than the control group （P〈0.05）. Conclusion Shisanwei Hezhong Pill combined with acupuncture can significantly improve the clinical symptoms of patients with FD of incoordination between liver and stomach and improve their quality of life.
作者
吴婧
张胜
刘礼梅
李学军
WU Jing ZHANG Sheng LIULi-mei LI Xue-jun(Department of Gastroenterology, The Second Affiliated Hospital of Anhui University of Chinese Medicine, Anhui Hefei 230061, China National Physician Outpatient Department, Anhui Univer- sity of Chinese Medicine, Anhui Hefei 230061, China)
出处
《安徽中医药大学学报》
2017年第3期53-56,共4页
Journal of Anhui University of Chinese Medicine
基金
安徽省卫生计生委中医药科研课题(2016zy25)
关键词
功能性消化不良
肝胃不和
十三味和中丸
针刺
Functional dyspepsia
Incoordination between liver and stomach
Shisanwei Hezhong Pill
Acupuncture
