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肥大细胞和脑神经炎症相关疾病 被引量:5

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摘要 1890年,Neumann首次在多发性脑硬化患者的脑硬化斑块边缘发现肥大细胞(Mast cells,MCs)。大量实验表明脑部MCs分泌或活化释放的物质参与脑内炎症反应以及神经系统炎症的病理过程,如自闭症谱系障碍、多发性脑硬化和阿尔兹海默症。自闭症谱系障碍(Autism spectrum disorder,ASD)是一种和神经炎症有关的神经发展性障碍,患者的交流和行为存在缺陷。
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2017年第5期793-795,F0003,共4页 Chinese Journal of Immunology
基金 常州大学人才引进基金(ZMF14020066) 常州科技局国际交流研究基金(KYJ1520305)资助
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