摘要
目的探讨夜间氧疗联合噻托溴铵对老年慢性阻塞性肺疾病(COPD)合并呼吸衰竭患者肺功能及生活质量的影响。方法选取64例COPD合并呼吸衰竭老年患者,将应用常规治疗和夜间氧疗32例患者作为对照组,将应用夜间氧疗和噻托溴铵联合医治32例患者作为观察组,对2组临床效果、肺功能及生活质量进行分析。结果观察组动脉血氧分压、动脉血二氧化碳分压均显著优于对照组,改良医学研究学会呼吸困难指数(MMRC)评分显著低于对照组,6 min步行距离显著长于对照组(P<0.05)。观察组治疗后肺功能改善效果、总体健康评分显著优于对照组(P<0.05)。结论 COPD并呼吸衰竭老年者应用夜间氧疗和噻托溴铵联合医治效果满意。
Objective To explore the effect of nocturnal oxygen therapy combined with tiotropium bromide on pulmonary function and quality of life in elderly patients with chronic obstructive pulmonary disease （COPD） and respiratory failure. Methods A total of 64 elderly patients with COPD and respiratory failure were selected. The 32 patients treated with conventional treatment and nocturnal oxygen therapies were designed as control group, and the other 32 patients treated with nocturnal oxygen therapy and tiotropium bromide were designed as observation group. The clinical effect, pulmonary function and quality of life were compared between the two groups. Results After treat- ment, the p（ O2 ） , p（ CO2 ） , score of MMRC and 6-minute walking distance in the observation group were significantly better than the control group （P 〈 0.05 ）. Improvement of pulmonary function and total healthy score in the observation group were significantly better than the control group （P 〈 0.05）. Conclusion Nocturnal oxygen therapy combined with tiotropium bromide is effective in treatment of elderly patients with COPD and respiratory failure.
出处
《实用临床医药杂志》
CAS
2017年第9期31-34,共4页
Journal of Clinical Medicine in Practice
基金
湖北省自然科学基金项目(2015CFB55)
关键词
呼吸衰竭
慢性阻塞性肺疾病
老年
夜间氧疗
噻托溴铵
生活质量
respiratory failure
chronic obstructive pulmonary disease
elderly
nocturnal oxygen therapy
tiotropium bromide
quality of life
