摘要
目的讨论HE4联合CA125及CA199在卵巢肿瘤早期诊断中的价值。方法采用酶联免疫吸附法检测50例卵巢癌、50例良性卵巢肿瘤及40例健康体检者的肿瘤标志物,分析各肿瘤标志物对卵巢癌早期诊断的价值。结果卵巢癌组中HE4、CA125及CA199的表达水平高于对照组,差异具有统计学意义(P<0.05);3种肿瘤标志物联合检测的敏感性与诊断效率分别提高到90.00%和85.00%。结论 HE4、CA125及CA199联合检测可以提高卵巢癌的早期诊断的效率。
Objective To clarify the value of combined detection of HE4, CA125 and CA 199 in diagnosis of ovarian cancer. Methods Tumor markers were measured by an ELASA method in 50 patients with ovarian cancer, 50 patients with benign ovarian diseases and 40 healthy people. Diagnostic values for early ovarian cancer were analyzed. Results Expressions of HE4, CA125 and CA199 in ovarian cancer were significantly higher than those incontrol group, and the differences were statistically significant （P 〈 0.05）. The sensitivity and diagnostic efficiency for ovarian cancer of the combined detection were enhanced to 90.00% and 85.00% respectively. Conclusion The combined detection of HE4, CA125 and CA199 could enhance the early diagnosis of ovarian cancer.
出处
《中国卫生标准管理》
2017年第11期114-116,共3页
China Health Standard Management
