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探讨奥美拉唑和泮托拉唑分别联合阿莫西林治疗胃溃疡的临床效果 被引量:12

The Clinical Efficacy of Omeprazole or Pantoprazole Combined With Amoxicillin in the Treatment of Gastric Ulcer
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摘要 目的研究分析胃溃疡使用奥美拉唑和泮托拉唑分别联合阿莫西林治疗的效果,为临床药物选择提供依据。方法 2013年2月—2014年2月对我院76例胃溃疡患者进行了研究分析,将患者分组为对照组和观察组,均有38例,对照组使用奥美拉唑和阿莫西林联合治疗,观察组使用泮托拉唑联合阿莫西林治疗,比较分析两组的临床治疗效果。结果观察组的治疗有效率比对照组高(P<0.05),1年随访调查显示,观察组的复发病例是2例,复发率5.26%,对照组的复发病例是6例,复发率15.79%,观察组的1年复发率比对照组低(χ~2=5.887,P<0.05)。结论胃溃疡采取阿莫西林和泮托拉唑联合治疗的效果比阿莫西林和奥美拉唑联合治疗要优秀,复发率较低。 Objeetive To study the efficacy of omeprazole or pantoprazole combined with amoxicillin in the treatment of gastric ulcer, and to provide evidence for clinical drug selection. Methods from February 2013 to February 2014, 76 cases of patients with gastric ulcer were studied in our hospital. Patients were divided into control group and observation group, 38 cases in each group. The control group was treated with omeprazole and amoxicillin for the treatment, the observation group used pantoprazole combined with amoxicillin treatment, Comparative analysis of two groups of clinical therapeutic effect. Results The effective rate of the observation group was higher than in the control group (P 〈 0.05), according to one year of follow-up, the observation group was 2 cases of recurrence, the recurrence rate was 5.26%, the control group was 6 cases of recurrence, the recurrence rate was 15.79%, the observation group recurrence rate was lower than the control group (Z2=5.887, P 〈 0.05). Conclusion Amoxiciliin and pantoprazole combined therapy is better than amoxicillin and omeprazole in the treatment of gastric ulcer, has low recurrence rate.
作者 段文杰
出处 《中国卫生标准管理》 2017年第11期100-101,共2页 China Health Standard Management
关键词 奥美拉唑 泮托拉唑 阿莫西林 omeprazole pantoprazole amoxicillin
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