摘要
目的研究食管癌患者术后使用鼻饲流质辅助肠内营养(EN)支持,对营养状况和胃肠道耐受性的影响。方法采用信封法将90例接受食管手术的患者随机分为研究组和对照组,每组45例。研究组患者给予鼻饲EN乳剂,同时鼻饲流质;对照组仅单独给予鼻饲EN乳剂。分别于术前和术后第7天,采用PG-SGA量表筛查恶性肿瘤营养风险指标(包括人血白蛋白、前白蛋白、乳酸脱氢酶、尿素、总胆固醇和血红蛋白水平),并比较两组患者的术后胃肠道功能指标。结果术后第7天,研究组患者的肿瘤营养风险指标水平均高于对照组,差异有统计学意义(P<0.05)。研究组患者腹胀、腹泻的发生率低于对照组,肛门排气开始时间早于对照组,差异均有统计学意义(P<0.05);但两组患者恶心、呕吐的发生率比较差异均无统计学意义(P>0.05)。结论鼻饲流质辅助EN能较好地改善食管癌围手术期患者的营养状况,提高胃肠道耐受性,是一种安全有效的治疗方法。
Objective To study the effect of the nasal fluids assisted enteral nutrition on Gastrointestinal tolerability and nutritional status of esophageal perioperative patients. Methods According to random number table, 90 patients with esophageal surgery were divided into research group （n= 45） and control group （n = 45）, The study group was provided with enteral nutrition emulsion, while nasal fluids. The control group was only provided with enteral nutrition emulsion. The trial period was 7 days. The basic demographic data and clinical information, metabolic markers of Hepatic function and nutrition metabolism were observed. Results On the 7th day after surgery, the level of tumor nutrition risk in the study group was higher than that in the control group （P〈0 . 05） . The comparison of gastrointestinal tolerability, the anal exhaust time was earlier than the control group ; the difference incidence of diarrhea and distention of the study group and the control group patients were significant （P〈0. 05）. However, the incidence of nausea and vomiting in the two groups was not statistically significant （P〉0.05） , Conclusions Enteral nutrition auxiliary nasogastric liquid is able to improve the nutritional status of the patients and the gastrointestinal tolerance is good. It is a safe and effective treatment.
作者
施庆彤
刁亚利
姚光怀
Shi Qingtong Diao Yali Yao Quanghnai(Department of Thoraic Surgery Department of Gastroenterology, The Affiliated Hospital of Yangzhou University, Yangzhou 22500, China)
出处
《中华胸部外科电子杂志》
2017年第2期87-91,共5页
CHINESE JOURNAL OF THORACIC SURGERY：Electronic Edition
关键词
食管癌
鼻饲流质
肠内营养
胃肠道耐受性
Esophageal
Nasal fluids
Gastrointestinal tolerance： Enteral nutrition
Perioperation
