期刊文献+

左外叶小儿活体肝移植术后血流动力学变化及其对术后短期肝功能的影响 被引量:3

Hemodynamic alteration and its impact on short-term liver function in children after living donor liver transplantation with adult-donated left lateral liver lobe
原文传递
导出
摘要 目的 探讨左外叶小儿活体肝移植术后门静脉、肝动脉血流变化及其与术后短期肝功能恢复的关系.方法 收集2006年6月-2013年3月在重庆医科大学附属儿童医院实施左外叶活体肝移植的17例患儿的临床资料.术后1~7天采用彩色多普勒超声诊断仪测定门静脉、肝动脉血流,检测患儿肝功能指标.分析门静脉、肝动脉血流变化趋势及与术后短期肝功能恢复的相关性.结果 (1)肝动脉血流量、血流量指数以及门静脉血流量、血流量指数变化与时间无关(P>0.05);肝动脉血流量、血流量指数与门静脉血流量、血流量指数变化无明显相关性(P>0.05);(2)移植物体重比(GRWR)与术后5、6、7天肝动脉血流量变化明显相关(P <0.05);GRWR与术后3~7天肝门静脉血流量变化明显相关(P<0.05);(3)术后第5天肝动脉血流量与同期AST变化呈负相关(r=-0.495,P<0.05);第3天及第5天门静脉血流量与同期AST变化呈负相关(r值分别为-0.525、-0.581,均P<0.05).结论 左外叶小儿活体肝移植术后肝动脉、门静脉血流量随GRWR增大明显增加;门静脉血流及肝动脉血流变化与术后短期肝功能恢复两者无明显相关性. Objective To investigate the hemodynamic changes in the portal veins and hepatic arteries and in liver functions after left lateral section living donor liver transplantation (LDLT) in children.Methods The clinical data of 17 patients who underwent LDLT using the left lateral section from June 2006 to March 2013 were analyzed.The portal venous flow,hepatic arterial flow and liver functions were studied by color Doppler and laboratory tests from 1 to 7 days after the operations.The data were analyzed with SPSS 20.0.Results (1) There were no significant correlations between the hepatic arterial flow (HAF),hepatic arterial flow index (HFI),portal venous flow (PVF) or portal venous flow index (PFI) with time (P 〉 0.05).There was also no significant correlation between the HAF (HFI) with PVF (PFI) (P 〉 0.05);(2) However,the graft recipient body weight ratio (GRWR) was significantly correlated with HAF on post operative days (POD) 5,6 and 7 (P 〈 0.05),and also with PVF on POD 3-7 (P 〈 0.05);(3) There were no significant correlations between HAF and AST on POD 3 (r =-0.495,P 〈 0.05),and between PVFandASTonPOD3 and5 (r=-0.525,-0.581,P〈0.05).Conclusions PVF and HAF increased significantly with GRWR after operation.There was no significant correlation between PVF,HAF and liver function in this study.
出处 《中华肝胆外科杂志》 CSCD 北大核心 2017年第5期300-303,共4页 Chinese Journal of Hepatobiliary Surgery
关键词 血流动力学 肝移植 肝动脉血流量 门静脉血流量 Hemodynamics Liver transplantation Hepatic arterial flow Portal venous flow
  • 相关文献

参考文献5

二级参考文献66

  • 1武红涛,唐缨.术中超声诊断左外叶活体肝移植门静脉血栓1例[J].中国超声医学杂志,2008,24(S1):108-109. 被引量:3
  • 2唐少珊,崔东旭,王晓光,刘守君.阻力指数在诊断肝移植术后肝动脉狭窄中的意义[J].中华超声影像学杂志,2006,15(3):236-237. 被引量:7
  • 3郑珊,王歧宏,肖现民,陆国平,董岿然,樊嘉,周俭,邱双健,吴志全.婴幼儿亲体部分肝移植[J].中华小儿外科杂志,2006,27(5):244-247. 被引量:13
  • 4Sandeep V, Manjiri D, Orpheus K, et al. Liver transplantation: vascular complications [J]. Ultrasound Quarterly, 2007, 23(4): 239-253 被引量:1
  • 5Pastacaldi S, Teixeira R, Montalto P, et al. Hepatic artery thrombosis after orthotopic liver transplantation: a review of nonsurgical canses[J]. Liver transplantation, 2001, 7(2): 75-81 被引量:1
  • 6De Gaetano AM, Cotroneo AR, Maresca G, et al. Color Doppler sonography in the diagnosis and monitoring of arterial complications after liver transplantation[J]. J Clin Ultrasound, 2000, 28(8): 373-380 被引量:1
  • 7Garcia-Criado A, Gilabert R, Nicolau C, et al. Early detection of hepatic artery thrombosis after liver transplantation by Doppler ultrasonography: prognostic implication[J]. J Ultrasound Med, 2001, 20(1): 51-58 被引量:1
  • 8Herold C, Reck T, Ott R, et al. Contrast-enhanced ultrasound improves hepatic vessel visualization after orthotopic liver transplantation[J]. Abdom Imaging, 2001, 26(6): 597-6(10 被引量:1
  • 9Nolten A, Sproat IA. Hepatic artery thrombosis after liver transplantation: temoral accuracy of diagnosis with duplex US and the syndrome of impending thrombosis[J]. Radiology, 1996, 198(2): 553-559 被引量:1
  • 10Propeck PA, Scanlan KA. Reversed or absent hepatic arterial diastolic flow in liver transplants shown by duplex sonography: a poor predictor of subsequent hepatic artery thrombosis[J]. Am J Roentgenol, 1992, 159 (2): 1199-1201 被引量:1

共引文献5

同被引文献12

引证文献3

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部