摘要
以蓖麻油酸和乙二醇丁醚为原料,经酯化、酰化两步反应合成了乙酰化蓖麻油酸丁氧基乙酯。运用正交实验与单因素实验确定酯化和酰化反应的最佳条件:酯化反应中,蓖麻油酸与乙二醇丁醚物质的量比为1∶1.15,催化剂一水合硫酸氢钠用量为蓖麻油酸质量的2%,反应时间为5h,反应温度为90℃,蓖麻油酸丁氧基乙酯的酯化率可达98.8%;酰化反应中,蓖麻油酸丁氧基乙酯与醋酐物质的量比为1∶1.2,催化剂对甲苯磺酸用量为蓖麻油酸丁氧基乙酯质量的3%,反应温度为80℃,反应时间为2h,酰化率达93.2%。采用红外光谱(FTIR)、质谱(HRMS)表征并确认了合成产物的化学结构。
Using ricinoleic acid and butyl cellosolve（BCS） as raw materials,2-butoxyethyl acetyl ricinoleate was synthesized by a two-step reaction of esterification and acylation. Through orthogonal experiment and single factor experiment, the optimal conditions were obtained as follows： for the esterification reaction, the molar ratio of ricinoleic acid to BCS 1 ： 1.15,dosage of catalyst NaHSO4 · H2O 2% （based on the mass of ricinoleic acid） ,reaction time 5 h and reaction temperature 90 ℃, the esterification rate of ricinoleic acid ethyl butoxy reached 98.8% ;for the acylation reaction,the molar ratio of ricinoleic acid ethyl butoxy to acetic anhydride 1 ： 1.2, dosage of catalyst p-toluenesulfonic acid 3 % （based on the mass of ricinoleic acid ethyl butoxy）, reaction temperature 80 ℃ and reaction time 2 h,the acylation rate reached 93.2%. The chemical structure of the syn- thesized product was characterized by FTIR and HRMS.
出处
《化学与生物工程》
CAS
2017年第5期12-16,共5页
Chemistry & Bioengineering
基金
国家林业局948项目(2015-4-55)
江苏高校优势学科建设工程项目
