摘要
目的:探讨生长抑素联合泮托拉唑对急性重症胰腺炎患者腹内高压与肠黏膜屏障功能的影响。方法:随机把60例急性重症胰腺炎患者分为治疗组和对照组,对照组应用常规综合治疗,治疗组在此基础上应用生长抑素联合泮托拉唑治疗,比较两组临床疗效。结果:治疗组治疗后二胺氧化酶、D-乳糖以及腹内高压水平均要显著低于对照组与治疗前(P<0.05);治疗组临床总有效率是93.3%,对照组临床总有效率是76.7%,组间临床疗效对比存在显著差异(P<0.05)。结论:生长抑素联合泮托拉唑对急性重症胰腺炎患者的腹内高压与肠黏膜屏障功能有积极影响,可显著改善患者肠道黏膜功能以及腹内高压水平。
Objective To investigate the somatostatin combined diazepam tora azole intra - abdominal pressure in patients with severe acute pancreatitis and the influence of the intestinal mucosal barrier function. Method 60 cases of acute severe pan-creatitis in our hospital were randomly divided into treatment group and control group, The control group received routine compre-hensive treatment, the treatment group based on the application of somatostatin combined with pantoprazole treatment, the clinical efficacy was compared between the two groups. Results The treatment group after treatment, D - galactose and diamine oxidase internal high pressure levels were significantly lower than the control group and before treatment （P 〈0. 05） ;Treatment group to-tal effective rate was 93. 3% and control group in clinical total effective rate was 76.1% ,the clinical curative effect comparison was significant difference between groups （P 〈 0. 05 ）. Conclusion There is a positive effect of intra - abdominal hypertension and intestinal mucosal barrier function of somatostatin combined with pantoprazole in patients with severe acute pancreatitis, can be significantly improved in patients with intestinal mucosal function and level of intra - abdominal hypertension.
出处
《吉林医学》
CAS
2017年第5期841-843,共3页
Jilin Medical Journal
关键词
生长抑素
泮托拉唑
重症胰腺炎
肠黏膜屏障功能
Somatostatin
Pantoprazole
Severe Acute Pancreatitis
Intestinal Mucosal Barrier Function
