摘要
目的探讨卡孕栓联合缩宫素用于瘢痕子宫产妇经第二次剖宫产术止血的临床效果。方法选择2014年12月~2016年10月间收治的90例瘢痕子宫二次剖宫产产妇作为研究对象,按入组顺序将其分为对照组和观察组,每组45例,对照组产妇采用缩宫素进行治疗,观察组产妇给予卡孕栓联合缩宫素治疗,对比并统计两组患者术中、术后出血量,术中凝血指标变化及术后不良反应发生情况。结果对照组产妇产后出血发生率为15.5%,观察组产妇产后出血发生率为(4.4%),差异有统计学意义(P<0.05);与对照组相比,观察组产妇术中、术后2 h、术后24 h出血情况均明显较低,差异具有统计学意义(P<0.05);观察组产妇术中凝血指标与对照组相比,亦具有显著优势(P<0.05);两组产妇术后不良反应发生率无明显区别(P>0.05),且均无严重不良反应。结论采用卡孕栓联合缩宫素预防和治疗瘢痕子宫二次剖宫产产后出血具有良好的临床疗效,可显著降低术中、术后产妇出血,且安全性较高,值得临床采用。
Objective To explore the hemostasis effect of methyl carprost suppository plus oxytocin on scaruterus after second cesarean section. Methods 90 cases of scaruterus after second cesarean section from Dec. 2014 to Oct. 2016 in our hospital were selected and divided into control group （n = 45） and observation group （n = 45） randomly. The cases in control group were taken oxytocin and the cases in observation group were taken methyl carprost suppository plus oxytocin. The blood loss during operation and after operation, change of coagulation index during operation and complications were compared. Results The occurrence rate of blood loss after operation in control group was 15.5% and that in observation group was 4.4%. The differences between the two groups were significant （P 〈 0.05 ）. The blood loss during operation, 2h after operation and 24h after operation were lower than that in control group. The difference was statistically significant （P 〈 0.05 ） .The coagulation indexin observation group had more significant advantages than control group （P 〈 0.0.5 ） . There was no significant difference of complications between the two groups （P 〉 0.05）. Conclusion Taken methyl carprost suppository plus oxytocin onscaruterus after second cesarean section has between effect and the therapy can reduce the blood loss during operation and after operation with strong security. It is worth applying in clinical medicine.
出处
《中国处方药》
2017年第5期66-67,共2页
Journal of China Prescription Drug
关键词
卡孕栓
缩宫素
联合治疗
瘢痕子宫二次剖宫产
产后出血
Methyl carprost suppository
Oxytocin
combination therapy
Scaruterus after second cesarean section
Postpartum hemorrhage
