摘要
的 调查脱发患者生活质量与抑郁状态及其影响因素,为改善其生活质量采取相应临床对策提供依据。方法 采用皮肤病生活质量指数(DLQI)和流行病学研究中心抑郁量表(CES?D),对雄激素性脱发和斑秃脱发患者237例进行问卷调查,评估其生活质量与抑郁状况,使用方差分析和logistic回归分析其影响因素。结果 237例脱发患者收集到有效答卷218份,218例脱发患者DLQI量表均分为9.1 ± 5.4,总体上脱发对生活质量的影响为中度影响,重度及以上影响者占38.07%。CES?D量表均分为14.8 ± 9.9,有抑郁倾向者占37.61%。DLQI得分和CES?D得分呈正相关(r = 0.29,P 〈 0.01)。单因素方差分析结果显示,不同年龄、性别、文化程度及就诊次数对DLQI得分差异无统计学意义。多因素logistic回归分析显示,脱发患者发生抑郁倾向的危险因素有:就诊次数(OR = 1.81,95% CI:1.21 ~ 2.69)和DLQI影响程度(OR = 1.08,95% CI:1.03 ~ 1.13)。结论 脱发不仅影响患者生活质量,而且给患者心理带来负面影响。
Objective To assess the quality of life, prevalence of depression and their influencing factors in patients with alopecia, to investigate, and to provide evidences for relevant clinical therapeutic strategies to improve patients′ quality of life. Methods A questionnaire survey was carried out in 237 patients with androgenetic alopecia or alopecia areata, and their quality of life and depression were measured using dermatology life quality index (DLQI) and center for epidemiologic studies depression scale(CES-D), respectively. Factors influencing the quality of life and depression were analyzed by analysis of variance and logistic regression analysis. Results Among 237 patients with alopecia, 218 questionnaires were eligible with the mean score of DLQI being 9.1 ± 5.4. Alopecia had a moderate effect on the quality of life in general, and 38.07% of the patients were severely affected. The mean score of CES-D was 14.8 ± 9.9, and 37.61% of the patients showed depressive tendency. The DLQI score was positively correlated with CES-D score (r = 0.29, P 〈 0.01). One-way analysis of variance (ANOVA) showed that the DLQI score was not affected by age, gender, education level or the number of visits. Multivariate logistic regression analysis revealed that the risk factors for depressive tendency in patients with alopecia were the number of visits (OR = 1.81, 95% CI: 1.21 - 2.69) and DLQI score (OR = 1.08, 95% CI: 1.03 - 1.13). Conclusion Alopecia not only affects the quality of life, but also mental states of patients.
出处
《中华皮肤科杂志》
CAS
CSCD
北大核心
2017年第5期360-363,共4页
Chinese Journal of Dermatology
基金
杭州市卫生科技计划项目(2013A25)
关键词
秃发
斑秃
问卷调查
生活质量
抑郁
Alopecia
Alopecia areata
Questionnaires
Quality of life
Depression