摘要
液体活检在实现精准医疗的过程中已经崭露头角，其在多种疾病诊疗的应用实践中起到正越来越重要的作用。结直肠癌发病率高、起病隐匿，基于液体活检的精准检测技术将有利于早期筛查与诊断、术后监测以及靶向用药指导，最终可改善患者生存质量及预后。我们应把握当下机遇，推动具有潜力的研究成果向结直肠癌临床诊疗应用的转化。临床医师、检验技术人员及监管机构应直面液体活检技术在临床转化过程中的各项挑战。
Liquid biopsy plays an important role in the process of precision medical treatment. Its clinical value in the diagnosis and treatment of various diseases has being constantly proved. Colorectal cancer with high incidence begins subtly. The applicaiton of efficient early screening and diagnostic methods can effectively reduce the disease damage, and the implementation of precise post-operative and medication monitoring as the guidance for therapeutic strategy is helpful to improve the prognosis of patients. We should seize the opportunity to promote the transformation of research findings into the clinical application of colorectal cancer. Clinicians, technicians and regulators should face up and work together to overcome the challenges met during the process of clinical liquid biopsy.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2017年第4期227-230,共4页
Chinese Journal of Laboratory Medicine
基金
上海市卫生计生系统重要薄弱学科建设项目（2015ZB0201）
关键词
结直肠肿瘤
肿瘤标记
生物学
DNA
肿瘤
肿瘤细胞
循环
Colorectal neoplasms
Tumor markers, biological
DNA, neoplasm
Neoplastic cells, circulating
