摘要
目的:探讨不同病理类型早期宫颈癌ADC值的差异及其临床意义。方法:选取131例经病理及临床证实为早期宫颈癌的患者,其中鳞癌100例、腺癌17例、腺鳞癌14例。100例鳞癌中低分化4例、中分化87例、高分化7例。所有患者治疗前行3.0T MR常规扫描及DWI检查。测量病灶的ADC值,比较不同病理分型及不同分化程度早期宫颈癌的ADC值的差异。结果:早期宫颈鳞癌与腺癌的ADC均值、最小值之间的差异有统计学意义(P<0.01),早期宫颈腺癌与腺鳞癌的ADC均值、最小值之间的差异有统计学意义(P<0.01)。分化程度不同的早期宫颈鳞癌之间ADC均值的差异无统计学意义(P>0.05)。结论:ADC值在术前评估早期宫颈癌的病理类型方面有一定价值,但对其分化程度的术前评估价值有限。
Objective：The purpose of this study was to analyze the differences of ADC value of early cervical cancer in different histologic types and their clinical significance. Methods： One hundred and thirty-one patients with early cervical cancer confirmed by pathology and clinical data were included in this study. There were 100 cases with cervical squamous cell carcinoma （CSCCs） ,17 cases with cervical adenocarcinoma （CACs） and 14 cases with cervical adeno-squamous carcinoma （CASCs）. Among 100 CSCCs, poorly differentiated 4 cases,moderately differentiated 87 cases,and well differentiated 7 cases. All patients underwent 3.0T MR both routine scan and DWI examination. ADC values of the tumors were obtained, and the mean （ADC ） ,maximum （ADCnl=x） and minimum （ADCml,） values were calculated. The difference of ADC values of early cervical cancer with different histologic types and different differentiation degrees was analyzed. Results：There was significant difference in the ADC and ADCmi, between early CSCCs and CACs （both P〈0.01） and between early CACs and ASCs （P〈0.01）. There was no significant difference in ADC of CSCCs among different differentiation grades （P〉 0.05）. Conclusion： ADC value has certain predictive roles in preoperative evaluation of histologic types for early cervical cancer,but it has limitation in distinguishing different differentiation degrees.
出处
《放射学实践》
北大核心
2017年第4期328-331,共4页
Radiologic Practice
基金
国家公益性行业科研专项基金(201402020)
关键词
宫颈癌
磁共振成像
表观扩散系数
病理学
分化程度
Cervical cancer
Magnetic resonance imaging
Apparent diffusion coefficient
Pathology
Differentiation degree
