摘要
目的探讨基于MRI T2WI及增强序列的纹理分析在鉴别直肠经典型腺癌、部分黏液腺癌及黏液腺癌中的价值。方法回顾性分析41例经手术病理证实的直肠腺癌患者临床及影像资料,依据病理将其分为直肠经典型腺癌组22例、部分黏液腺癌组11例和黏液腺癌组8例。使用ITK-SNAP软件在横轴位T2WI和动态增强序列上以肿瘤实性成分最大层面为中心,连续三层进行ROI手动勾画。将勾画好的ROI文件导入美国GE公司AK软件内,利用不同的纹理参数进行特征提取,从而得到肿瘤内部的纹理特征值。选取熵、偏度、峰度等纹理参数作为分析指标。采用SPSS软件中的单因素方差分析、LSD-t及Kruskal-Wallis检验对3组数据间进行两两比较,分析3组之间纹理参数差异是否有统计学意义。结果增强序列中的纹理参数熵、偏度、峰度、均匀度、均值及T2WI序列中的纹理参数平均值、偏度和峰度3组数据之间的两两比较中差异无统计学意义(P>0.05);T2WI序列中的纹理参数熵、均匀度和标准差在鉴别经典型腺癌组、部分黏液腺癌组及黏液腺癌组的两两比较中差异均有统计学意义(P<0.05)。结论cMRI联合纹理分析在鉴别直肠经典型腺癌、直肠黏液腺癌和部分黏液腺癌中存在一定的价值,其中纹理分析在鉴别直肠经典型腺癌和部分黏液腺癌中具有较大的临床意义。
Objective To explore the value of texture analysis based on T2WI and contrast-enhancement sequence of MRI in distinguishing rectal mucinous adenocarcinoma from partial mucinous adenocarcinoma and mucinous adenocarcinoma.Methods The clinical and imaging data of 41 patients with pathologically confirmed rectal cancer were analyzed retrospectively.They were divided into three groups according to different pathologyresults,the 22 cases of classic rectal adenocarcinoma,11 cases of partial mucinous adenocarcinoma and 8 cases of mucinous adenocarcinoma.ITK-SNAP software was applied to draw ROI manually in three consecutive layers on the T2WI and dynamic-enhancement sequence with the largest solid component of tumor as the center.The ROI file was imported into the AK software of GE company,and different texture parameters are used to extract features,so as to get the texture feature of the tumor.Entropy,skewness,kurtosis,etc were selected as parameter indexes.The SPSS software’s one-way ANOVA analysis,LSD-t test and Kruskal-Wallis test were used to compare the data of three groups,thenanalysed whether there was statistical difference among the three groups of texture parameters.Results There was no significant difference(P>0.05)among the mean values,skewness and kurtosis on the contrast-enhancement sequence and the mean value,skewness and kurtosis on the T2WI sequence in the differential diagnosis of classic adenocarcinoma,partial mucinous adenocarcinoma and mucinous adenocarcinoma whereas the difference was significant(P<0.05)among the entropy,uniformity and standard deviation on the T2WI sequence of the three groups,respectively.Conclusion cMRI combined with texture analysis can help to distinguish classic rectal adenocarcinoma,mucinous adenocarcinoma and partial mucinous adenocarcinoma.Besides,texture analysis has great clinical significance in the differentiation of classic rectal adenocarcinoma and partial mucinous adenocarcinoma.
作者
王裴培
王婷婷
方昕
李乃玉
吴瑶媛
林婷婷
董江宁
WANG Peipei;WANG Tingting;FANG Xin(Department of Imaging,the First Affiliated Hospital of University of Science and Technology of China(Anhui Provincial Hospital),Hefei,Anhui Province 230031,P.R.China)
出处
《临床放射学杂志》
北大核心
2021年第3期536-540,共5页
Journal of Clinical Radiology
关键词
直肠
经典型腺癌
黏液腺癌
纹理分析
磁共振成像
Rectum
Classic adenocarcinoma
Mucinous adenocarcinoma
Texture analysis
Magnetic resonance imaging
