摘要
目的探讨血清超敏C-反应蛋白(hs-CRP)、甲胎蛋白(AFP)、癌胚抗原(CEA)、铁蛋白(Fer)联合检测鉴别诊断肝癌与肝脏良性疾病的应用价值。方法选择42例肝癌患者为肝癌组,40例肝脏良性疾病患者为良性组,42例健康体检者为健康组。检测三组hs-CRP、AFP、CEA、Fer水平,比较三种检测方案对肝癌的诊断效果。结果肝癌组hs-CRP、AFP、CEA、Fer水平均高于良性组和健康组,差异有统计学意义(P<0.05)。四种指标联合检测灵敏度为94.35%(117/124),准确度为80.49%(66/82),均高于另两种检测。结论血清蛋白联合检测可提高诊断灵敏度和准确度,值得临床推广应用。
Objective To investigate the value of combined detection of high sensitive C-reactive protein（hs-CRP）, al- pha fetoprotein（ AFP）, carcinoma embryonic antigen（ CEA）, ferritin（Fer） in differential diagnosis of hepatocellular carci- noma （HCC） and benign liver disease. Methods Forty-two patients with HCC were selected as HCC group, 40 benign liver disease patients as benign group, 42 healthy subjects as health group. The level of hs-CRP, AFP, CEA, Fer in the three groups were detected,three detection for the diagnosis of hepatoma were compared. Results The level of hs-CRP, AFP, CEA, Fer in the HCC group were higher than those in the other two groups, the differences were significant （P 〈 0. 05）. The sensitivity of combined detection with four indexes was 94. 35% （117/124） , and tile accuracy was 80.49% （66/82） , which was higher than those of other two methods. Conclusion Combined detection of serum albumin can im- prove the diagnostic sensitivity and accuracy, it is worth of clinical application.
出处
《临床医学》
CAS
2017年第3期28-29,共2页
Clinical Medicine
关键词
肝癌
超敏C-反应蛋白
甲胎蛋白
铁蛋白
癌胚抗原
Hepatocellular carcinoma
High sensitive C-reactive protein
Alpha fetoprotein
Ferritin
Carcinoma em-bryonic antigen
