摘要
目的:探讨选择性神经根阻滞治疗腰椎间盘突出症疼痛的疗效及对血清疼痛及炎症介质的影响。方法:68例腰椎间盘突出症疼痛患者,回顾治疗方案并分为接受选择性神经根阻滞治疗的观察组35例、接受内科保守治疗的对照组33例。治疗1周后评估两组患者治疗效果,治疗前后检测血清疼痛介质、炎症介质含量。结果:治疗1周后,观察组的治疗总有效率高于对照组(P<0.05);观察组血清疼痛介质PGE2、HA、5-HT含量低于对照组,炎症介质IL-1、IL-6、TNF-α含量低于对照组(P<0.05)。结论:选择性神经根阻滞可提高腰椎间盘突出症疼痛的疗效,降低血清疼痛及炎症介质含量。
Objective：To investigate the effect of selective nerve root block in the treatment of lumbar disc herniation pain and its influence on serum pain and inflammatory mediators.Methods;68 patients with lumbar disc herniation pain were reviewed and divided into two groups,the observation group was treated with selective nerve root block,and the other group was treated with conservative treatment in35 cases（n=33）.After 1 weeks of treatment,the therapeutic effect of the treatment of the patients in the two groups was evaluated.Results：After 1 weeks of treatment,the total effective rate of observation group was higher than that of control group（P0.05）;the serum levels of PGE2,HA,5-HT pain medium was lower than the control group,IL-1,IL-6,inflammatory mediators TNF-content was lower than that of the control group（P0.05）.Conclusion;Selective nerve root block can improve the curative effect of lumbar disc herniation,and reduce the content of serum pain and inflammatory mediators.
出处
《中国医药导刊》
2017年第3期223-224,共2页
Chinese Journal of Medicinal Guide
关键词
腰椎间盘突出症疼痛
选择性神经根阻滞
疼痛介质
炎症介质
Lumbar intervertebral disc herniation pain
selective posterior rhizotomy
Pain mediators
Inflammatory mediators
