摘要
目的探讨子宫内膜癌术后盆腔淋巴囊肿形成的危险因素。方法收集2009年1月至2016年4月天津医科大学总医院妇产科行盆腔和(或)腹主动脉旁淋巴结切除的子宫内膜癌患者397例,术后发生淋巴囊肿者76例。结果子宫内膜癌盆腔和(或)腹主动脉旁淋巴结切除后淋巴囊肿的发生率为19.14%,单因素分析发现淋巴结切除范围、FIGO分期、术后化疗、术后放疗及术后放疗联合化疗与淋巴囊肿发生相关(P=0.002,P=0.010,P=0.046,P=0.040,P=0.030)。多因素Logistic回归分析,发现盆腔+腹主动脉旁淋巴结切除是淋巴囊肿形成的独立危险因素(P=0.014)。结论淋巴囊肿是子宫内膜癌盆腔和(或)腹主动脉旁淋巴结切除后的常见并发症,采取个体化治疗,避免不必要的大范围的淋巴结清扫,将会减少淋巴囊肿的发生。
Objective To investigate the incidence and risk factors of lymphocele development after pelvic lymphadenectomy.Methods This retrospective study was carried out on 397 patients who received a pelvic lymphadenectomy with or without a para-aortic lymphadenectomy between January 2009 and April 2016, due to endometrial cancer, in General Hostipal of Tianjin Medical University. A total of 76 patients developed lymphoceles. Results The incidence of lymphocele after a pelvic lymphadenectomy with or without a para-aortic lymphadenectomy was 19.14%. Single factor analysis indicated that scope of lymphadenectomy, FIGO stage, postoperative radiotherapy, postoperative chemotherapy, postoperative radiotherapy and chemotherapy were associated with lymphocyst formation （P= 0.002, P=0.010, P=0.046, P=0.040, P=0.030 respectively）. Multiple factors Logistic analysis through the adjustment of the factors showed a pelvic lymphadeneetomy with a para-aortic lymphadenectomy was the independent risk factors for lymphocyst formation （P=0.014）.Conclusion Lymphocele is the most common postoperative complication after a pelvic lymphadenectomy with para-aortic lymphadenectomy in endometrial cancers. It is useful to help reduce the incidence of lymphocele to perform individualized treatment and avoid unnecessary ltmphadenectomy of a large scope.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2017年第4期428-432,共5页
Chinese Journal of Practical Gynecology and Obstetrics
基金
国家自然科学基金(81272863
81572568)
