摘要
目的探讨CRP联合PCT在早期新生儿败血症诊断与治疗中的意义。方法选取我科60例健康新生儿作为对照组,新生儿败血症患儿60例为观察组,比较两组患者血清PCT与CRP的水平。结果以CRP>8 mg/L为参考值,以PCT>2 ng/ml为参考值,观察组CRP、PCT阳性率高于对照组,差异均具有统计学意义(P<0.01)。治疗后,观察组的血清PCT转阴、CRP水平与治疗前比较,差异具有统计学意义(P<0.05)。结论血清PCT联合CRP对新生儿败血症早期诊断有明确的临床意义,可动态监测其变化,有助于判断疾病的预后,协助临床有效应用抗生素。
Objective To investigate the significance of CRP combined with PCT in the diagnosis and treatment of early neonatal septicemia. Methods 60 cases of healthy neonates in our department were selected as control group, and a total of 60 cases of neonatal septicemia were selected as the observation group. The levels of serum PCT and CRP were compared between two groups. Results The reference value of CRP 〉 8 mg/L and PCT 〉2 ng/ml as reference value, the positive rate of CRP and PCT in the observation group was significantly higher than that in the control group, and the difference was statistically significant （P 〈 0.01）. After effective treatment, the observation group compared with negative serum PCT and CRP levels before and after treatment, the difference was statistically significant （P 〈 0.05）. Conclusion Serum PCT combined with CRP has clear clinical implications for early diagnosis of neonatal sepsis, which can dynamically monitor the changes, help to determine the disease prognosis, assist the clinical effective application of antibiotics.
出处
《中国卫生标准管理》
2017年第5期127-129,共3页
China Health Standard Management
