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原发性中枢神经系统淋巴瘤发病机制研究进展 被引量:8

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摘要 原发性中枢神经系统淋巴瘤(primary central nervous system lymphoma,PCNSL)是指原发于颅内、眼、脊髓和软脑膜等部位的非霍奇金淋巴瘤,并在明确诊断时,无中枢神经系统(central nervous system,CNS)以外淋巴结受累。由于CNS中不存在淋巴组织,因此PCNSL的确切发病机制尚不明确,目前比较流行的有两种假说,第一种假说认为PCNSL来源于外周淋巴细胞的恶性转化,依据是CNS原发和外周发生的淋巴瘤细胞免疫表型并无明显差别。
作者 程岗 张剑宁
出处 《中华神经外科疾病研究杂志》 CAS 2017年第2期190-192,共3页 Chinese Journal of Neurosurgical Disease Research
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