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胃癌免疫治疗机制及应用的研究进展 被引量:6

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摘要 胃癌是常见的恶性肿瘤之一,化疗以及分子靶向治疗所带来的生存期改善有限。免疫治疗是通过激发机体自身特异性抗肿瘤反应来抑制肿瘤的发生发展,是继手术、化疗及放疗后一种新的肿瘤治疗方法。免疫疫苗可以刺激发生起始的T淋巴细胞反应,免疫检查点抑制剂可以增强活性T淋巴细胞的效应,过继免疫治疗是通过回输体外扩增的肿瘤相关效应淋巴细胞从而达到抗肿瘤的效果。其中,免疫检查点抑制剂在胃癌治疗中表现出了一定的疗效,免疫检查点抑制剂联合应用或许是未来的一个研究方向。
机构地区 皖南医学院
出处 《山东医药》 CAS 北大核心 2017年第10期103-106,共4页 Shandong Medical Journal
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