摘要
目的:分析乌司他丁在脓毒血症患者临床治疗中的应用价值。方法:选取海丰县彭湃纪念医院2014年3月至2015年8月期间收治的66例脓毒血症患者,采用摸球法分为观察组和一般组,均对两组患者实施抗感染、维持内环境稳定的对症治疗,在上述治疗的基础上给予观察组患者乌司他丁治疗。结果:治疗前两组患者的血气指标状况、炎症因子(IL-1、IL-6、IL-8)表达水平比较,差异无统计学意义(P>0.05),治疗后观察组血气指标状况优于一般组,差异具有统计学意义(P<0.05),各炎症因子的表达水平均低于一般组,差异具有统计学意义(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论:乌司他丁在脓毒血症患者临床治疗中能够有效降低患者体内炎性因子的表达水平,改善患者血气指标,有效改善患者的预后。
Objective To analyze the effects of application on ulinastatin in the treatment of patients with sepsis in the treatment. Methods 66 cases of sepsis patients totally admitted to hospital in March 2014 to 2015 August as the research object, and 66 cases of patients were randomly divided into study group and the general group, were of two groups of patients with the implementation of anti infection, to maintain a stable environment for symptomatic treatment, study group patients with ulinastatin treatment on the basis of the treatment given. Results treatment of two groups of patients before blood gas index, inflammatory cytokines （IL-1, IL-6, IL-8）expression level showed no significant difference （P 〉 0.05）. After the treatment of patients with blood gas index is better than general group patients （P 〈 0.05）. Expression of various inflammatory factors were lower than the general group （P〈0.05）. There was no significant difference in the incidence of adverse reactions between the two groups （P〉0.05）. Conclusion Ulinastatin in the clinical treatment of patients with sepsis, reliable, less adverse reactions, can effectively improve the prognosis of patients.
出处
《深圳中西医结合杂志》
2017年第2期8-9,共2页
Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
