摘要
目的观察玉屏风散合消风散化裁治疗儿童春季角结膜炎(VKC)(风热挟湿证)的临床疗效。方法选取风热挟湿证VKC患儿66例按照随机数字表法分为两组,治疗组予玉屏风散合消风散化裁的中药汤剂内服,对照组患眼局部滴用富马酸依美斯汀滴眼液,均以7 d为1个疗程,连续治疗2个疗程,对比两组的临床疗效和治疗前后5项症状(眼痒、异物感、畏光、流泪、烧灼感)及6项体征(分泌物、结膜充血水肿、眼睑和球周组织水肿、睑结膜乳头与滤泡、角膜缘改变、角膜上皮改变)的改善情况。结果治疗组总有效率为93.75%,高于对照组的76.47%(P<0.05)。两组治疗后5项症状和6项体征与治疗前比较,差异有显著性统计学意义(P<0.01),且治疗后治疗组5项症状和6项体征改善程度均优于对照组(P<0.01)。结论玉屏风散合消风散化裁治疗儿童VKC(风热挟湿证)近期疗效明确、安全,有较好临床应用前景。
Objective： To observe the clinical efficacy of Yupinffeng powder combined with modified Xiaofeng powder treating vernal keratoconjunctivitis with wind-heat syndrome with dampness of Children. Methods ： Sixtyfour children patients with wind-heat syndrome with dampness were randomly divided into treatment group （n = 32） and the control group （n = 34）. Patients in treatment group were administrated by Yupingfeng powder combined with modified Xiaofeng powder while those in control group were given Emedastine Difumarate Eye Drops, with a course of treatment for 7 days and 2 periods of it. The clinical curative effect of two groups was compared and changes of the five symptoms （itching, foreign body sensation, photophobia, tearing, burning sensation） and six signs（secretions, hyperemia, edema of eyelid and peribulbar, tarsus papilla and follicle, limbus change, corneal epithelium change） in pretherapy and post-treatment were observed. Results： Total efficacy rate of the treatment group was 93.75%, while that of the control group was only 76.47%, the differences were statistically significant （P 〈 0.05）. Meanwhile,the five signs and six symptoms in both groups were better after treatment,the differences were statistically significant （all P〈 0.01 ）, and the changes of five signs and six symptoms in treatment group were significantly better than that of control group after treatment （P〈 0.01 ）. Conclusion： Yupingfeng powder combined with modified Xiaofeng powder is a curative and safe drug in treatment of vernal keratoconjunctivitis with wind-heat syndrome with dampness and has good clinical application prospects.
作者
黄仕尧
陈国孝
徐东
HUANG Shiyao CHEN Guoxiao XU Dong(Zhejiang Chinese Medical University ,Zhejiang,Hangzhou 310053 ,China.)
出处
《中国中医急症》
2017年第3期523-525,共3页
Journal of Emergency in Traditional Chinese Medicine
基金
浙江省中医药科技计划青年人才项目(2017ZQ014)
关键词
儿童
风热挟湿证
春季角结膜炎
中药
Children
Wind-heat syndrome with dampness
Vernal keratoconjunctivitis
Traditional Chinese medicine
