摘要
目的分析子宫动脉化疗栓塞治疗难治性妊娠滋养细胞肿瘤及肿瘤出血的临床疗效。方法 90例难治性妊娠滋养细胞肿瘤患者为研究对象,随机分为实验组与对照组,各45例。对照组采用常规方案进行治疗,实验组采用子宫动脉化疗栓塞治疗。比较两组患者的治疗效果、术中出血量、出血停止时间、治疗后1年复发情况。结果实验组患者总有效率93.33%高于对照组的60.00%,差异具有统计学意义(χ~2=13.975,P<0.05)。实验组患者术中出血量(272.45±1.74)ml少于对照组的(368.41±1.87)ml,差异具有统计学意义(t=252.013,P<0.05)。实验组患者出血停止时间(3.00±0.24)d短于对照组的(7.00±1.96)d,差异具有统计学意义(t=13.589,P<0.05)。治疗后1年,实验组复发率0低于对照组的15.56%,差异具有统计学意义(χ~2=7.590,P<0.05)。结论采用子宫动脉化疗栓塞治疗难治性妊娠滋养细胞肿瘤,可有效提升治疗效果,减少出血量,降低后期复发率,可广泛运用。
Objective To analyze the clinical effect of uterine artery chemotherapy embolism in the treatment of refractory pregnancy sertoli cell tumor and tumor bleeding. Methods A total of 90 patients with refractory pregnancy sertoli cell tumor and tumor bleeding as study subjects were randomly divided into experimental group and control group, with 45 cases in each group. The control group received conventional regimens for treatment, and the experimental group received uterine artery chemotherapy embolism for treatment. Comparison were made on treatment effect, intraoperative bleeding volume, bleeding stop time and recurrence after 1 year of treatment in two groups. Results The experimental group had higher total effective rate as 93.33% than 60.00% in the control group, and the difference had statistical significance（χ^2=13.975, P〈0.05）. The experimental group had less intraoperative bleeding volume as（272.45±1.74） ml than（368.41±1.87） ml in the control group, and the difference had statistical significance（t=252.013, P〈0.05）. The experimental group had shorter bleeding stop time as（3.00±0.24） d than（7.00±1.96） d in the control group, and the difference had statistical significance（t=13.589, P〈0.05）. After 1 year of treatment, the experimental group had incidence of recurrence as 0, which was lower than 15.56% in the control group, and the difference had statistical significance（χ^2=7.590, P〈0.05）. Conclusion Uterine artery chemotherapy embolism can effectively improve the treatment effect for the treatment of refractory pregnancy sertoli cell tumor, reduce bleeding volume and decreasing incidence of recurrence. So it can be widely used.
作者
王玉莹
WANG Yu-ying(Liaoning Province Yingkou City Economic and Technological Development Zone Central Hospital, Yingkou 115007, China)
出处
《中国实用医药》
2017年第3期69-71,共3页
China Practical Medicine
关键词
子宫动脉化疗栓塞
难治性妊娠滋养细胞肿瘤
肿瘤出血
Uterine artery chemotherapy embolism
Refractory pregnancy sertoli cell tumor
Tumor bleeding
