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小儿肺炎支原体感染后免疫功能变化的探讨 被引量:10

Study on the Changes of Immune Function in Children with Mycoplasma Pneumoniae Infection
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摘要 目的探讨小儿肺炎支原体感染与免疫功能变化的关系。方法随机选择2014年9月—2016年9月期间该院儿科收治的100例肺炎支原体感染患儿作为观察组,另选同期100名体检健康儿童作为对照组,对两组患儿的免疫因子水平进行检测和统计学分析。结果观察组的IgG、IgM、IgA、补体C3、补体C4、免疫复合物花环率、C3b受体花环率、免疫黏附促进因子、免疫黏附抑制因子等指标的体内平均含量分别为(1.25±0.08)、(1.09±0.22)、(10.35±2.13)、(1.02±0.32)、(0.29±0.07)、(5.32±1.13)、(10.36±1.08)、(52.65±5.23)、(30.22±2.31),对照组的各项指标含量分别为(1.66±0.13)、(1.36±0.17)、(13.02±2.64)、(1.51±0.33)、(0.54±0.09)、(7.86±1.23)、(14.00±0.98)、(71.02±5.64)、(21.08±2.19),各指标组间比较差异有统计学意义(P<0.05)。结论小儿肺炎支原体感染后,其免疫能力相对低下,改善其免疫状态有助于促进疾病恢复。 Objective To explore the relationship between mycoplasma pneumonia infection and immune function. Methods Random selection our hospital 100 cases of Mycoplasma pneumoniae infection in children as the observation group, and selected 100 healthy children as control group, the levels of immune factors in the two groups of children in the detection and analysis of statistics. Results The average content in the observation group IgG, IgM, IgA, complement C3, C4, immune complex rosette, C3 b receptor rosette, immune adhesion promoting factor, immune adherence inhibition factor respectively(1.25±0.08),(1.09±0.22),(10.35±2.13),(1.02±0.32),(0.29±0.07),(5.32±1.13),(10.36±1.08),(52.65±5.23),(30.22±2.31) and the control group respectively. The content of each index(1.66 ±0.13),(1.36 ±0.17),(13.02 ±2.64)(1.51 ±0.33).(0.54 ±0.09),(7.86±1.23),(14±0.98),(71.02±5.64),(21.08±2.19), each index comparison between groups was statistically significant(P0.05). Conclusion The children with Mycoplasma pneumoniae infection, the immune ability is relatively low, improve the immune state contribute to the recovery of the disease.
作者 柯红 邝咏云
出处 《中外医疗》 2017年第1期24-25,28,共3页 China & Foreign Medical Treatment
关键词 肺炎支原体 体液免疫 细胞免疫 免疫功能 Mycoplasma pneumonia Humoral immunity Cellular immunity Immune function
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