摘要
目的探讨脾氨肽口服冻干粉治疗小儿肺炎支原体感染的疗效及对免疫功能的影响。方法选取2011年4月至2015年4月我院收治的100例肺炎支原体感染患儿作为研究对象,采用随机数字表法将所选患儿分为研究组和对照组,每组各50例,对照组给予常规药物治疗,研究组在对照组的基础上加用脾氨肽口服冻干粉治疗,观察比较两组患儿的临床症状、体征恢复时间及治疗前后T淋巴细胞亚群变化情况。结果研究组患儿热退时间、咳嗽消失时间及肺部啰音消失时间均短于对照组(P<0.05);治疗后研究组患儿CD3^+、CD4^+及CD4^+/CD8^+均高于对照组,CD8^+低于对照组(P<0.05)。结论脾氨肽口服冻干粉治疗小儿肺炎支原体感染效果确切,可明显改善机体细胞免疫功能,促进患儿病情康复,值得临床推广使用。
Objective To explore the clinical effect of spleen aminopeptide oral lyophilized powder for the treatment of children with mycoplasma pneumoniae infection, and analyze the influence to immunity. Methods One hundred cases of children with mycoplasma pneumoniae infection were randomly divided into two groups equally. The control group received routine drug therapy, while the study group received spleen aminopeptide oral lyophilized powder on the basis of routine therapy. The recovery time of clinical symptoms and changes of T-lymphocyte subsets before and after treatment were compared. Results The fever clearance time, disappeared time of cough, and disappeared time of pulmonary rales of study group were significantly shorter than those of control group（P〈0.05）. After treatment, the levels of CD3＋,CD4＋and CD4＋/CD8＋of study group were significantly higher than those of control group, and the level of CD8＋was significantly lower than that of control group（P〈0.05）. Conclusions Spleen aminopeptide oral lyophilized powder has significant effect for the treatment of mycoplasma pneumoniae infection in children, which can effectively improve the immune function, and promote the recovery of disease.
出处
《临床医学工程》
2016年第3期317-318,共2页
Clinical Medicine & Engineering
关键词
脾氨肽口服冻干粉
肺炎支原体感染
细胞免疫功能
Spleen aminopeptide oral lyophilized powder
Mycoplasma pneumoniae infection
Cell immune function
