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脐带间充质干细胞移植治疗帕金森病5例

Umbilical Cord Mesenchymal Stem Cell Transplantation Treating Parkinson's Disease Among 5 Cases
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摘要 目的观察脐带间充质干细胞移植治疗帕金森病患者的疗效。方法选取2015年3月至2016年5月我院脑病科收治的帕金森病患者5例(男3例,女2例);平均年龄(68.23±9.13)岁。患者均签署知情同意书。静脉滴注脐带间充质干细胞200ml(含细胞数量为1×108个),3次为1个疗程,共3个疗程。结果 5例患者治疗3个疗程后,与治疗前相比,帕金森病评定量表评分、Hoehn-Yahr量表评分明显降低(P<0.01)。结论脐带间充质干细胞移植在改善帕金森病患者的临床症状有显著疗效。 Objective To observe the effects of umbilical cord mesenchymal stem cell transplantation in the treatment of patients with Parkinson’s disease curative effect .Methods A total of 2 0 1 5 March to may in 2 0 1 6 in our hospital department of encephalopathy treated patients with Parkinson’s disease in 5 cases(male 3 cases , female 2 ) ;mean age (6 8 .2 3 ± 9 .1 3 ) years old .The patients signed the informed consent .Intravenous infusion of umbilical cord mesenchymal stem cells (BMSCs) 2 0 0 ml (including cell number 1 × 1 0^8 ) ,3 times for a course of treatment ,a total of three courses .Results The 5 cases after 3 courses of treatment ,compared with before treatment ,Unified Parkinson’s disease rating scale and Hoehn - Yahr amount .Conclusion The umbilical cord mesenchymal stem cells transplantation in improving the clinical symptoms of patients with Parkinson’s disease has a significant effect on the clinical symptoms of’s disease .
出处 《内蒙古医学杂志》 2016年第9期1048-1049,共2页 Inner Mongolia Medical Journal
关键词 帕金森病 脐带间充质干细胞 移植 疗效 parkinson’s disease umbilical cord mesenchymal stem cells transplantation curative effect
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