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β2-微球蛋白、癌胚抗原和D-二聚体联合检测在恶性肿瘤诊断中的应用 被引量:7

Application of combined detections of β2-microglobulin, carcino-embryonic antigen and D-Dimer in diagnosis of malignant tumor
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摘要 目的:对恶性肿瘤患者的β2-微球蛋白(β2-MG)、癌胚抗原(CEA)及D-二聚体(D—Dimer)的变化进行研究,并探讨联合检测的临床意义。方法:选取2014年至2015年本院收治的245例恶性肿瘤患者(癌症组)的血清β2-MG、CEA及D-Dimer含量与200例健康对照组进行分析比较。结果:与健康对照组比较,癌症组的血清β2-MG、CEA及D-Dimer含量均明显增高,三者联合检测阳性率高于单一项目检测(P〈0.05)。结论:血清β2-MG、CEA及D-Dimer联合检测对恶性肿瘤患者的早期筛查诊断具有重要的临床价值。 Objective: The changes of β2-microglobulin (β2-MG) , carcino-embryonic antigen (CEA) and D- Dimer in patients with malignant tumor were detected, and the clinical significance of combined detection was discussed. Methods: The levels of serum β2-MG, CEA, and D-Dimer in 245 patients with malignant tumor (cancer group) from 2014 to 2015 were analyzed and compared with the 200 cases of healthy control group. Results: Compared with the healthy control group, the serum levels of β2-MG, CEA and D-Dimer in cancer group were significantly higher, and the positive rate of the three joint detection was higher than that of single item (P〈0.05) . Conclusion: The combined detection of serum β2-MG, CEA and D-Dimer has important clinical value for early screening and diagnosis of malignant tumor patients.
出处 《医学检验与临床》 2016年第9期19-20,47,共3页 Medical Laboratory Science and Clinics
关键词 恶性肿瘤 Β2-微球蛋白 癌胚抗原 D-二聚体 Malignant tumor β2-microglobulin Carcino-embryonic antigen D- Dimer
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