摘要
采用硅胶、Sephadex LH-20、MCI和半制备HPLC等色谱技术,对豆科云实属植物大托叶云实种子的95%乙醇提取物进行分离纯化。从中分离得到了5个卡山烷型二萜化合物,根据理化性质和波谱数据鉴定为3β-乙酰氧基-卡山烷-12,14(17),15-三烯-7β-醇(1)、caesalmin C(2)、caesall E(3)、caesalpinin MJ(4)和1-deacetylcaesalmin C(5),其中化合物1为新化合物,2、4、5首次从该植物中分离得到。
Five cassane diterpenes were isolated from the 95% ethanol extract of the seeds of Caesalpinia bonduc（Leguminosea） by a combination of various chromatographic methods,including silica gel,Sephadex LH-20,and semi-preparative HPLC. On the basis of spectroscopic techniques,their structures were identified as 3β-acetoxy-cassa-12,14（17）,15-trien-7β-ol（1）,caesalmin C（2）,caesall E（3）,caesalpinin MJ（4）,and 1-deacetylcaesalmin C（5）. Among them,compound 1 is a new compound and 2,4,5 were isolated from the plant for the first time.
出处
《药学学报》
CAS
CSCD
北大核心
2017年第2期279-282,共4页
Acta Pharmaceutica Sinica
基金
国家自然科学基金资助项目(21662023
21402212)
云南省教育厅基金研究生项目(2015J049)
