摘要
胰腺微循环障碍和缺血是急性胰腺炎起病阶段重要的病理生理改变,器官灌注不足是该病预后不良的危险因素。在入院后最初12~24 h液体复苏是急性胰腺炎早期最重要的内科治疗方法,及时而合理地补液有助于改善预后。但关于液体种类、输液速度及监测手段仍缺乏高质量的临床证据,有待更多的随机对照试验加以研究。
Microcirculation disturbance and ischemia of the pancreas are important pathophysiological changes in the onset of acute pancrea-titis,and organ hypoperfusion is a risk factor for poor prognosis.During the first 12 to 24 hours after admission,fluid resuscitation is the most important medical treatment for the early stage of acute pancreatitis,and timely and rational fluid infusion helps to improve prognosis. However,there lacks high -quality clinical evidence for type of fluid,infusion speed,and monitoring methods,and more randomized con-trolled trials are needed.
作者
吴东
钱家鸣
WU Dong QIAN Jiaming(Department of Gastroenterology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China)
出处
《临床肝胆病杂志》
CAS
2017年第1期12-16,共5页
Journal of Clinical Hepatology
关键词
胰腺炎
液体治疗
述评
pancreatitis
fluid therapy
editorial