摘要
目的:探讨广州地区中老年性骨质疏松症患者QCT骨密度与中医辨证分型的相关性。方法:在广州地区选取年龄为50岁以上符合纳入标准的骨质疏松症患者200例,应用TOSHIBA64排螺旋CT扫描机和配套的校准体模及骨密度分析软件进行腰椎骨密度定量CT(QCT)分析,并通过中医辨证进行分型,将所得数据进行统计学分析,探讨腰椎椎体的OCT骨密度值及其与中医辨证分型的相关性。结果:中老年骨质疏松患者骨量存在随年龄增长而逐渐降低的规律,而60~65岁年龄段骨量下降明显加速(P<0.01)。女性骨密度值峰值高于男性,而随年龄增长其值下降较迅速,65岁以后骨密度低于男性。根据骨质疏松的中医辨证分型:肾虚型共64例(32.0%),其中肾阴不足31例(15.5%)、肾阳虚衰33例(16.5%);脾肾两虚型42例(21.0%);肝肾阴虚型43例(21.5%);瘀血阻络型18例(9.0%);通过单因素方差分析,各型骨量减少程度差异无统计学意义(P>0.05)。结论:广州地区老年性骨质疏松患者椎体骨密度减低存在随时间递减的规律,证候分型亦有一定规律可循,但其与骨密度之间无显著相关性,可能与样本量较少、地区单一等因素有一定关系,尚需在日后研究中进一步探讨。
Objective： This paper aims to discuss the correlation between elderly individuals＇ BMD with QCT and TCM syndrome types in Guang Zhou area. Methods ： The BMD in every vertebra of lumbar spine was investigated by QCT（Toshiba＇ s 64-slice CT） in 200 patients（100 male, 100 female） above the age of 50 in Guangzhou area and TCM syndrome types will also be analyzed. The correlation between BMD with QCT and TCM syndrome types will be discussed according to the statistics results. Results： The BMD of elderly individuals＇ declined with aging and the BMD was predominantly declined in group of 60 to 65 years（p〈0.01）.The PBM（peak bone density）of female is higher than male,but the BMD of female declined more quickly with aging and female＇ s BMD was lower than the male＇ s after 65 years old. According to the results of TCM syndrome types, 64 patients （32%） were kidney-deficiency type, 31 patients （15.5%） were kidney-yin deficiency type, 33 patients （16.5%） were kidney-yang deficiency, 42patients （21%） were spleen and kidney deficiency, 43patients （21.5%） were liver and kidney yin deficiency and 18 patients （9%） were blood stasis type. Results of one-way analysis of variance showed the BMD decline of each type had no statistics difference. Conclusions： Through the investigation, BMD＇ s decline of elderly individuals＇ in Guangzhou slows down with aging and tcm syndrome can also be typed. But there is on obvious correlation between them. Small sample size and singular sample area may account for the results and it will be studied in further exploration.
作者
陈时洪
陈国健
孙正平
李建安
李松涛
CHEN Shi-hong CHEN Guo-jian SUN Zheng-ping LI Jian-an LI song-tao(Guangdong 2nd TCM Hospital, Guangzhou ,Guangdong 510095 GuangDong 999Brain Hospital, Guangzhou, Guangdong,510510)
出处
《按摩与康复医学》
2017年第2期51-53,共3页
Chinese Manipulation and Rehabilitation Medicine
基金
广东省中医药局科研课题
编号:20142017
关键词
骨质疏松症
中医辨证分型
骨密度
相关性
Osteoporosis
TCM syndrome differentiation
bone mineral density
quantitative CT
correlation
