摘要
目的探析鼻咽癌调强放疗前后MRI影像变化及在疗效评估中的应用价值。方法以我院2012年1月~2014年8月收治50例鼻咽癌患者进行研究,所有患者均行调强放疗并于治疗前后进行MRI检查,统计治疗有效率、对比纤维化与复发患者放疗后MRI曲线斜率。结果治疗前T1WI呈等信号、T2WI高信号、DWI图像呈高信号。治疗后T2WI呈非均匀高信号、T1WI呈低信号,DWI序列呈信号减低,边界较治疗前清晰,增强扫描表现为不均匀强化。放疗治疗有效率92.0%(46/50),纤维化组斜率明显低于复发组(P<0.05)。结论 MRI检查可准确显示肿瘤范围而勾画放射治疗靶区,根据肿瘤形态的改变评价调强放疗效果,并对复发与纤维化进行鉴别,对鼻咽癌临床疗效及预后评估具有明显价值,值得推广。
Objective To explore the changes of MRI images before and after intensity modulated radiotherapy for nasopharyngeal carcinoma and the application value in efficacy evaluation. Methods 50 patients with nasopharyngeal carcinoma who were admitted into the hospital during January 2012 to August 2014 were studied. All patients were treated with intensity modulated radiotherapy and received MIni examination before and after the treatment. The treatment effective rate was statistiacally analyzed. The slope of MRI curve was compared between fibrosis and recurrent patients after radiotherapy. Results Before the treatment, uniform signal was on T1WI, high signal on T2WI of and high signal on DWI images. After the treatment, uneven high signal was on T2WI, low signal on T1WI and signal decreasing on DWI sequence. The boundary was clearer than that before the treatment and the enhanced scan showed inhomogeneous enhancement. The effective rate of radiotherapy was 92.0%（46/50）. The slope of the fibrosis group was significantly lower than that of the recurrence group and the difference was statistically significant （P 〈0.05）. Conclusion The application of MRI in nasopharyngeal carcinoma can be used to accurately display the range of tumor and radiotherapy target region. According to the change of tumor morphology, the effect of intensity modulated radiotherapy is evaluated. Recurrence and fibrosis are differentiated. It is of significant value in the evaluation of clinical curative effect and prognosis of nasopharyngeal carcinoma, which is worthy of promotion.
作者
曹传华
余海英
CAO Chuan-hua YU Hai-ying.(Department of Ontology, XiangYang Central Hospital, Xiangyang 441201, Hubei Province, China)
出处
《中国CT和MRI杂志》
2017年第2期45-47,共3页
Chinese Journal of CT and MRI
关键词
鼻咽癌
调强放疗
MRI
评估
Nasopharyngeal Carcinoma
Intensity Modulated Radiation Therapy
MRI
Evaluation
