摘要
目的:研究丁姜和胃贴膏组方药物挥发性成分超临界CO_2提取最佳工艺。方法:以萃取率和丁香酚含量为指标,采用L9(34)正交设计试验方案,考察萃取温度、萃取压力及萃取时间对组方药物丁香、砂仁、生姜的影响。结果:超临界CO_2提取最佳条件为:萃取温度46℃,萃取压力35 MPa,萃取时间2.5 h。此时萃取物萃取率为3.916%,丁香酚含量为28.688%(m L/g)。结论:该工艺简便、高效,可为优化丁姜和胃贴膏的制备工艺提供参数。
Objective：To study the optimal extraction technology for the volatile components from Dingjiang Hewei plaster by SFE-CO_2. Methods：Using the extraction rate and the content of eugenol as the indicators,L9（34） orthogonal design was applied to study the effects of extraction temperature,extraction pressure and extraction time on Flos Caryophylli,Fructus Amomi,and Rhizoma Zingiberis Recens. Results：Extraction rate of extract was 3.916% and the content of eugenol was 28.688%（m L/g） under the optimal extraction process：extraction temperature at 46 ℃,extraction pressure at 35 MPa and extraction during being 2.5 hr. Conclusion：This extracting technology is simple and efficient,and this study could provide parameters to optimize the processing technology of Dingjiang Hewei plaster.
作者
王友凤
曹云飞
张伟
WANG Youfeng CAO Yunfei ZHANG Wei(Shandong University of Traditional Chinese Medicine,Jinan 250355,China Qingdao Haici Medical Group, Qingdao 266033 ,China)
出处
《山东中医杂志》
2016年第12期1067-1070,共4页
Shandong Journal of Traditional Chinese Medicine
基金
青岛市2014年度医药科研指导计划(编号:2014-W JZD058)
